Oncolytic Avian Reovirus σA-Modulated Upregulation of the HIF-1α/C-myc/glut1 Pathway to Produce More Energy in Different Cancer Cell Lines Benefiting Virus Replication

Our previous reports proved that the structural protein σA of avian reovirus (ARV) is an energy activator which can regulate cellular metabolism that is essential for virus replication. This study has further demonstrated that the ARV protein σA is able to upregulate the HIF-1α/myc/glut1 pathway in...

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Bibliographic Details
Published in:	Viruses
Main Authors:	Chao-Yu Hsu, Jing-Wen Huang, Wei-Ru Huang, I-Chun Chen, Ming-Shan Chen, Tsai-Ling Liao, Yu-Kang Chang, Muhammad Munir, Hung-Jen Liu
Format:	Article
Language:	English
Published:	MDPI AG 2023-02-01
Subjects:	avian reoviruses oncolytic virus glycolysis c-myc HIF-1α glut1
Online Access:	https://www.mdpi.com/1999-4915/15/2/523

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