Alkaloid-based nanodrug delivery systems: An emerging strategy against drug-resistant bacterial wound infections

Bacterial infections significantly impede wound healing. With the escalating crisis of antimicrobial resistance, conventional antibiotics increasingly fail to meet the clinical demands for treating wounds infected with resistant strains. Plant-derived alkaloids have emerged as promising alternatives...

Full description

Bibliographic Details
Published in:	International Journal of Pharmaceutics: X
Main Authors:	Jiajun Wu, Xuebo Li, Yuqi Zeng, Shenghui Hou, Nairong Yao, Bo Yang, Qiyue Yang, Xiaolin Dai
Format:	Article
Language:	English
Published:	Elsevier 2026-06-01
Subjects:	Alkaloid Nanodrug delivery system Bacteria Wound
Online Access:	http://www.sciencedirect.com/science/article/pii/S2590156726000897

Similar Items

Nanodrug delivery systems targeting ferroptosis as an innovative therapeutic approach for Rheumatoid Arthritis
by: Xiaolin Dai, et al.
Published: (2025-06-01)

Advances in therapeutic nanodrug delivery systems for infectious lung diseases: a review
by: Gang Sheng, et al.
Published: (2022-08-01)

Research Progress of Osimertinib Supported by Nanodrug Delivery System Against Non-small Cell Lung Cancer
by: LIU Rugui, et al.
Published: (2024-02-01)

Nanodrug Delivery Systems for Direct Clearance or Neutralization of LPS
by: Chen L, et al.
Published: (2025-07-01)

Biomembrane-Modified Biomimetic Nanodrug Delivery Systems: Frontier Platforms for Cardiovascular Disease Treatment
by: Yunan Gu, et al.
Published: (2024-08-01)

Advances in tumor immunomodulation based on nanodrug delivery systems
by: Bo Wang, et al.
Published: (2023-12-01)

Global trends and research hotspots in nanodrug delivery systems for breast cancer therapy: a bibliometric analysis (2013–2023)
by: Yang Li, et al.
Published: (2025-03-01)

The Role of Integrins for Mediating Nanodrugs to Improve Performance in Tumor Diagnosis and Treatment
by: Chi Yu, et al.
Published: (2023-05-01)

The clinical regimens and cell membrane camouflaged nanodrug delivery systems in hematologic malignancies treatment
by: Yuanyuan Liu, et al.
Published: (2024-04-01)

An orally administered bacterial membrane protein nanodrug ameliorates doxorubicin cardiotoxicity through alleviating impaired intestinal barrier
by: Zhen Li, et al.
Published: (2024-07-01)

Enhanced nanodrug delivery in tumors after near-infrared photoimmunotherapy
by: Inagaki Fuyuki F., et al.
Published: (2019-09-01)

Nanodrugs used in cancer therapy
by: Katerina Kopeckova, et al.
Published: (2019-06-01)

Mesoporous nanodrug delivery system: a powerful tool for a new paradigm of remodeling of the tumor microenvironment
by: Yinhui Hang, et al.
Published: (2023-03-01)

Self-carrier nanodrugs with dual antibacterial agents to overcome tobramycin resistance in multidrug-resistant Staphylococcus aureus
by: Ya-nan Fu, et al.
Published: (2026-02-01)

Poor prognosis outcome tumors, bacteria-infected tumors and nanodrugs: current evidence and hypotheses towards a paradigm change for treatment
by: Henk J. Busscher, et al.
Published: (2026-04-01)

Efficiently targeted therapy of glioblastoma xenograft via multifunctional biomimetic nanodrugs
by: Zhipeng Yao, et al.
Published: (2022-12-01)

Advancements in Nanodrug Delivery Systems as Controlled-Release Systems for Glaucoma Therapy: An Inspirational Step Toward Translation from Research to Clinic
by: Tanin Hosseinkhani, et al.
Published: (2026-05-01)

Nanodrug with ROS and pH Dual‐Sensitivity Ameliorates Liver Fibrosis via Multicellular Regulation
by: Liteng Lin, et al.
Published: (2020-04-01)

Supramolecular self-assembly of EGCG-selenomethionine nanodrug for treating osteoarthritis
by: Haichao Yu, et al.
Published: (2024-02-01)

Nanodrugs Targeting T Cells in Tumor Therapy
by: Maximilian Haist, et al.
Published: (2022-05-01)

Carrier-free nanodrugs with efficient drug delivery and release for cancer therapy: From intrinsic physicochemical properties to external modification
by: Heng Mei, et al.
Published: (2022-02-01)

A combined miR-34a and arsenic trioxide nanodrug delivery system for synergistic inhibition of HCC progression after microwave ablation
by: Jian Hu, et al.
Published: (2021-11-01)

Edge advances in nanodrug therapies for osteoarthritis treatment
by: Jinfeng Liao, et al.
Published: (2024-10-01)

Peptide-anchored neutrophil membrane-coated biomimetic nanodrug for targeted treatment of rheumatoid arthritis
by: Ni Yang, et al.
Published: (2023-01-01)

Twins‐like nanodrugs synchronously transport in blood and coalesce inside tumors for sensitive ultrasound imaging and triggerable penetrative drug delivery
by: Yujun Cai, et al.
Published: (2024-06-01)

From basic to clinical translation: advances and perspectives of photodynamic nanodrugs
by: Shitang Ma, et al.
Published: (2025-05-01)

Editorial: Engineering Nucleic Acids-Based Functional Nanomaterials, Nanodrugs, and Biosensors
by: Jabrane Jouha, et al.
Published: (2022-06-01)

Drug Repurposing of Lactoferrin Combination in a Nanodrug Delivery System to Combat Severe Acute Respiratory Syndrome Coronavirus-2 Infection
by: Assem Barakat, et al.
Published: (2021-07-01)

Cerium Dioxide–Dextran Nanocomposites in the Development of a Medical Product for Wound Healing: Physical, Chemical and Biomedical Characteristics
by: Ekaterina V. Silina, et al.
Published: (2024-06-01)

Controllable loading and release of nanodrugs in polymeric vesicles
by: Junwei Zhou, et al.
Published: (2022-12-01)

In Situ and Real‐Time Multi‐Modality Imaging Guided Orderly Triple‐Therapy of Tumors with a Multifunctional Nanodrug
by: Chaoyi Yang, et al.
Published: (2025-07-01)

Hybrid Inorganic-Organic Core-Shell Nanodrug Systems in Targeted Photodynamic Therapy of Cancer
by: Gauta Gold Matlou, et al.
Published: (2021-10-01)

Nanodrugs Manipulating Endoplasmic Reticulum Stress for Highly Effective Antitumor Therapy
by: Yuting Xiang, et al.
Published: (2022-07-01)

Multicomponent coassembled nanodrugs based on ovalbumin, pheophorbide a and Zn2+ for in vitro photodynamic therapy
by: Xiaoyan Ma, et al.
Published: (2022-12-01)

Application of Computing as a High-Practicability and -Efficiency Auxiliary Tool in Nanodrugs Discovery
by: Ke Xu, et al.
Published: (2023-03-01)

Fabrication of Ginsenoside-Based Nanodrugs for Enhanced Antitumor Efficacy on Triple-Negative Breast Cancer
by: Shuting Zuo, et al.
Published: (2022-08-01)

Current trends and future perspectives of stroke management through integrating health care team and nanodrug delivery strategy
by: Xuelu Han, et al.
Published: (2023-11-01)

RGD-based self-assembling nanodrugs for improved tumor therapy
by: Bin Wang, et al.
Published: (2024-10-01)

Development of Nanodrug for Treatment of Breast Cancer Using Mallotus Tetracoccus Leaves-Standardisation, Synthesis and Characterisation
by: Ramalakshmi Subbiah, et al.
Published: (2016-06-01)

A celastrol-based nanodrug with reduced hepatotoxicity for primary and metastatic cancer treatmentResearch in context
by: Min Zhou, et al.
Published: (2023-08-01)