Anesthesia promotes acute expression of genes related to Alzheimer’s disease and latent tau aggregation in transgenic mouse models of tauopathy

Abstract Background Exposure to anesthesia in the elderly might increase the risk of dementia. Although the mechanism underlying the association is uncertain, anesthesia has been shown to induce acute tau hyperphosphorylation in preclinical models. We sought to investigate the impact of anesthesia o...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:	Molecular Medicine
المؤلفون الرئيسيون:	John David Eun, Heidy Jimenez, Leslie Adrien, Adam Wolin, Philippe Marambaud, Peter Davies, Jeremy L. Koppel
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	BMC 2022-07-01
الموضوعات:	Alzheimer’s disease Anesthesia Isoflurane Tau Hyperphosphorylation Neuroinflammation
الوصول للمادة أونلاين:	https://doi.org/10.1186/s10020-022-00506-4

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