DNA repair synthesis and histone deposition partner during homologous recombination

Chromatin remodeling is critical for the regulation of the DNA damage response. We highlight findings from our recent study showing that the deposition of the histone variant H3.3 by the alpha-thalassemia mental retardation X-linked protein (ATRX) and the death domain associated protein (DAXX) chrom...

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书目详细资料
发表在:Molecular & Cellular Oncology
Main Authors: Amira Elbakry, Szilvia Juhász, Arthur Mathes, Markus Löbrich
格式: 文件
语言:英语
出版: Taylor & Francis Group 2018-09-01
主题:
double-strand breaks
homologous recombination
repair synthesis
chromatin remodeling
atrx
daxx
h3.3
在线阅读:http://dx.doi.org/10.1080/23723556.2018.1511210
实物特征
总结:Chromatin remodeling is critical for the regulation of the DNA damage response. We highlight findings from our recent study showing that the deposition of the histone variant H3.3 by the alpha-thalassemia mental retardation X-linked protein (ATRX) and the death domain associated protein (DAXX) chromatin remodeling complex regulates DNA repair synthesis during homologous recombination.
ISSN:2372-3556

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