Molecular Epidemiology of Fonsecaea Species

To assess population diversities among 81 strains of fungi in the genus Fonsecaea that had been identified down to species level, we applied amplified fragment-length polymorphism (AFLP) technology and sequenced the internal transcribed spacer regions and the partial cell division cycle, β-tubulin,...

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Bibliographic Details
Published in:Emerging Infectious Diseases
Main Authors: Mohammad Javad Najafzadeh, Jiufeng Sun, Vania A. Vicente, Corne H.W. Klaassen, Alexandro Bonifaz, A.H.G. Gerrits van den Ende, Steph B.J. Menken, G. Sybren de Hoog
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2011-03-01
Subjects:
Chromoblastomycosis
Fonsecaea
distribution
amplified fragment-length polymorphism
AFLP
fungi
Online Access:https://wwwnc.cdc.gov/eid/article/17/3/10-0555_article
Description
Summary:To assess population diversities among 81 strains of fungi in the genus Fonsecaea that had been identified down to species level, we applied amplified fragment-length polymorphism (AFLP) technology and sequenced the internal transcribed spacer regions and the partial cell division cycle, β-tubulin, and actin genes. Many species of the genus Fonsecaea cause human chromoblastomycosis. Strains originated from a global sampling of clinical and environmental sources in the Western Hemisphere, Asia, Africa, and Europe. According to AFLP fingerprinting, Fonsecaea isolates clustered in 5 groups corresponding with F. pedrosoi, F. monophora, and F. nubica: the latter 2 species each comprised 2 groups, and F. pedrosoi appeared to be of monophyletic origin. F. pedrosoi was found nearly exclusively in Central and South America. F. monophora and F. nubica were distributed worldwide, but both showed substantial geographic structuring. Clinical cases outside areas where Fonsecaea is endemic were probably distributed by human migration.
ISSN:1080-6040
1080-6059

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