Validating remote cognitive tests in the Wisconsin Registry for Alzheimer's Prevention

Abstract INTRODUCTION Remote cognitive assessment addresses barriers to research participation for older participants, but continuity in longitudinal studies is a challenge. We examined whether scores from telephone‐based assessments (T‐COG) were valid and reliable estimates of in‐person traditional...

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Bibliographic Details
Published in:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Main Authors: Erin M. Jonaitis, Rachel L. Studer, Bailey Wheelock, Mary E. Murphy, Caitlin A. Artz, Rachel N. Weinberg, Sterling C. Johnson, Bruce P. Hermann, Kimberly D. Mueller, Rebecca E. Langhough
Format: Article
Language:English
Published: Wiley 2025-07-01
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Online Access:https://doi.org/10.1002/dad2.70153
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Summary:Abstract INTRODUCTION Remote cognitive assessment addresses barriers to research participation for older participants, but continuity in longitudinal studies is a challenge. We examined whether scores from telephone‐based assessments (T‐COG) were valid and reliable estimates of in‐person traditional neuropsychological findings. METHODS Participants in the Wisconsin Registry for Alzheimer's Prevention (WRAP) who had completed in‐person testing within the prior 12 months were invited to complete a follow‐up T‐COG visit. Bland–Altman plots and intraclass correlations were used to assess repeatability and bias. RESULTS Correlations between in‐person and T‐COG scores were of moderate to large magnitude (Pearson r: 0.57 to 0.80, intraclass correlation coefficients: 0.52 to 0.79). Bland–Altman plots revealed moderately wide limits of agreement, but no clear bias. DISCUSSION The WRAP‐abbreviated T‐COG battery can be completed in less than an hour and shows good concordance with in‐person test administration. Availability of the T‐COG option may reduce missing data and/or enhance retention when obstacles to in‐person attendance arise. Highlights Remote testing had adequate validity compared to in‐person assessment. A telephone preclinical Alzheimer's composite correlated well with the original. Remote options may reduce missing data when barriers exist to in‐person testing. Teleassessment may facilitate participant recruitment and retention.
ISSN:2352-8729