Synthesis of new derivatives of 1-(3-aminophenyl)-4-benzoyl-5-phenyl-1H-pyrazole-3-carboxylic acid

1-(3-Aminophenyl)-4-benzoyl-5-phenyl-1H-pyrazole-3-carboxylic acid (1) was synthesized according to the literature. 2-(3-Aminophenyl)-2,6-dihydro-3,4-diphenyl-7H-pyrazolo[3,4-d]pyridazin-7-one (5) was obtained by the cyclocondensation reaction of 1 with hydrazine hydrate. New pyrazole derivatives of...

Full description

Bibliographic Details
Published in:Journal of the Serbian Chemical Society
Main Authors: RAHMI KASIMOGULLAR, BELMA ZENGIN, MAKBULE MADEN, SAMET MERT, CAVIT KAZAZ
Format: Article
Language:English
Published: Serbian Chemical Society 2010-12-01
Subjects:
pyrazole-3-carboxylic acid
pyridazin
diazonium salts
cyclocondensation
Online Access:http://www.shd.org.rs/JSCS/Vol75/No12/02_4909_4082.pdf
Description
Summary:1-(3-Aminophenyl)-4-benzoyl-5-phenyl-1H-pyrazole-3-carboxylic acid (1) was synthesized according to the literature. 2-(3-Aminophenyl)-2,6-dihydro-3,4-diphenyl-7H-pyrazolo[3,4-d]pyridazin-7-one (5) was obtained by the cyclocondensation reaction of 1 with hydrazine hydrate. New pyrazole derivatives of compounds 1 and 5 were synthesized by their reaction with β-diketones, β-ketoesters, β-naphthol, phenol and various other reagents. The structures of the synthesized compounds were characterized by 1H-NMR, 13C-NMR, IR and mass spectroscopy, as well as elemental analysis.
ISSN:0352-5139

Similar Items