Mechanisms of reduced efficacy of HER2-targeted therapy in HER2-low breast cancer by long-term nicotine exposure in patient-derived xenograft mouse tumor models

The effects of long-term nicotine exposure on the treatment of HER2-positive breast cancer have only been studied epidemiologically, leaving the molecular mechanisms unclear. Therefore, it's challenging for clinicians to devise effective treatments based on this correlation. Our investigation e...

書誌詳細
出版年:	Ecotoxicology and Environmental Safety
主要な著者:	Yu-Hsuan Lin, Yuan-Soon Ho, Bu-Miin Huang, You-Cheng Liao, Tzu-Chun Cheng, Ying-Chi Lin, Shih-Hsin Tu, Yun Yen, Li-Ching Chen
フォーマット:	論文
言語:	英語
出版事項:	Elsevier 2025-04-01
主題:	α9-nAChR HER2 Smoking Breast cancer Herceptin resistance Patient-derived xenograft
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S0147651325004075

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