Simvastatin retards cartilage degradation and subchondral bone deterioration induced by a high-fat diet in mice

ABSTRACTTo evaluate the effects of simvastatin on the degeneration of cartilage and subchondral bone in a mice model of osteoarthritis (OA) induced by obesity. Thirty male 3-month-old C57BL/6J mice were randomized into three groups: mice with normal diet + vehicle (distilled water) (Control), mice w...

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Bibliographic Details

Published in:	CyTA - Journal of Food
Main Authors:	Hetong Li, Faming Tian, Yu Gou, Yunpeng Hu, Qiangqiang Lian, Liu Zhang
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2023-12-01
Subjects:	Osteoarthritis obesity cartilage subchondral bone simvastatin
Online Access:	https://www.tandfonline.com/doi/10.1080/19476337.2023.2245008