A novel quinoline with airway relaxant effects and anti-inflammatory properties
Abstract Background In chronic pulmonary diseases characterized by inflammation and airway obstruction, such as asthma and COPD, there are unmet needs for improved treatment. Quinolines is a group of small heterocyclic compounds that have a broad range of pharmacological properties. Here, we investi...
| Published in: | Respiratory Research |
|---|---|
| Main Authors: | Jesper Bergwik, Jielu Liu, Médea Padra, Ravi K. V. Bhongir, Lloyd Tanner, Yujiao Xiang, Mia Lundblad, Arne Egesten, Mikael Adner |
| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-03-01
|
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12931-024-02780-8 |
Similar Items
Toll-like receptor activation induces airway obstruction and hyperresponsiveness in guinea pigs
by: Yujiao Xiang, et al.
Published: (2024-11-01)
by: Yujiao Xiang, et al.
Published: (2024-11-01)
Prenatal Maternal Lipopolysaccharide and Mild Newborn Hyperoxia Increase Intrapulmonary Airway but Not Vessel Reactivity in a Mouse Model
by: Margaret E. Kuper-Sassé, et al.
Published: (2021-03-01)
by: Margaret E. Kuper-Sassé, et al.
Published: (2021-03-01)
Pharmacological OGG1 inhibition decreases murine allergic airway inflammation
by: Lloyd Tanner, et al.
Published: (2022-10-01)
by: Lloyd Tanner, et al.
Published: (2022-10-01)
Pharmacological inhibition of MutT homolog 1 (MTH1) in allergic airway inflammation as a novel treatment strategy
by: Anna Adler, et al.
Published: (2025-03-01)
by: Anna Adler, et al.
Published: (2025-03-01)
Zoledronic Acid Targeting of the Mevalonate Pathway Causes Reduced Cell Recruitment and Attenuates Pulmonary Fibrosis
by: Lloyd Tanner, et al.
Published: (2022-06-01)
by: Lloyd Tanner, et al.
Published: (2022-06-01)
<i>Adenophora Stricta</i> Root Extract Alleviates Airway Inflammation in Mice with Ovalbumin-Induced Allergic Asthma
by: Cheol-Jong Jung, et al.
Published: (2023-04-01)
by: Cheol-Jong Jung, et al.
Published: (2023-04-01)
Evaluation of Epworth Sleepiness Scale in Patients with Bronchial Hyperreactivity without Airway Obstruction
by: Fatma Merve Tepetam
Published: (2018-04-01)
by: Fatma Merve Tepetam
Published: (2018-04-01)
High-fat Western diet alters crystalline silica-induced airway epithelium ion transport but not airway smooth muscle reactivity
by: Janet A. Thompson, et al.
Published: (2024-01-01)
by: Janet A. Thompson, et al.
Published: (2024-01-01)
Viola odorata Alleviates Airway Inflammation and Histopathological Changes in an Animal Model of Allergic Asthma
by: Moones Fallah, et al.
Published: (2024-10-01)
by: Moones Fallah, et al.
Published: (2024-10-01)
Relationship Between Potassium Ion Channels and Airways Defence Reflexes Influenced by Experimentally Induced Allergic Inflammation in Guinea Pigs
by: Kocmalova M., et al.
Published: (2012-02-01)
by: Kocmalova M., et al.
Published: (2012-02-01)
Hyperreactivity of the bronchi in children, whooping cough convalescents
by: Yu. V. Nesterova, et al.
Published: (2020-10-01)
by: Yu. V. Nesterova, et al.
Published: (2020-10-01)
Male rats emit aversive 44-kHz ultrasonic vocalizations during prolonged Pavlovian fear conditioning
by: Krzysztof Hubert Olszyński, et al.
Published: (2024-12-01)
by: Krzysztof Hubert Olszyński, et al.
Published: (2024-12-01)
Hyperimmune malarial splenomegaly in a malaria-endemic area of southwest Burkina Faso: case of Bobo-Dioulasso
by: Zoungrana Jacques, et al.
Published: (2024-08-01)
by: Zoungrana Jacques, et al.
Published: (2024-08-01)
TLR7 promotes chronic airway disease in RSV-infected mice
by: Mark A. Miles, et al.
Published: (2023-09-01)
by: Mark A. Miles, et al.
Published: (2023-09-01)
CFTR dysfunction in smooth muscle drives TGFβ dependent airway hyperreactivity
by: Elizabeth L. Kramer, et al.
Published: (2023-08-01)
by: Elizabeth L. Kramer, et al.
Published: (2023-08-01)
Anti-Asthmatic Effects of Saffron Extract and Salbutamol in an Ovalbumin-Induced Airway Model of Allergic Asthma
by: Pranav Nair, et al.
Published: (2021-01-01)
by: Pranav Nair, et al.
Published: (2021-01-01)
Inhaling arsenic aggravates airway hyperreactivity by upregulating PNEC-sourced 5-HT in OVA-induced allergic asthma
by: Xue Lu, et al.
Published: (2025-01-01)
by: Xue Lu, et al.
Published: (2025-01-01)
Increased Vocalization of Rats in Response to Ultrasonic Playback as a Sign of Hypervigilance Following Fear Conditioning
by: Krzysztof H. Olszyński, et al.
Published: (2021-07-01)
by: Krzysztof H. Olszyński, et al.
Published: (2021-07-01)
Vitamin A deficiency alters the pulmonary parenchymal elastic modulus and elastic fiber concentration in rats
by: Holmes Amey J, et al.
Published: (2005-07-01)
by: Holmes Amey J, et al.
Published: (2005-07-01)
Protective Effects of Korean Herbal Remedy against Airway Inflammation in an Allergic Asthma by Suppressing Eosinophil Recruitment and Infiltration in Lung
by: Soyon Yoon, et al.
Published: (2020-12-01)
by: Soyon Yoon, et al.
Published: (2020-12-01)
Substrate-specific binding of 8-oxoguanine DNA glycosylase 1 (OGG1) reprograms mucosal adaptations to chronic airway injury
by: Lang Pan, et al.
Published: (2023-08-01)
by: Lang Pan, et al.
Published: (2023-08-01)
The Changes in Expression of Na<sub>V</sub>1.7 and Na<sub>V</sub>1.8 and the Effects of the Inhalation of Their Blockers in Healthy and Ovalbumin-Sensitized Guinea Pig Airways
by: Michaela Kocmalova, et al.
Published: (2021-07-01)
by: Michaela Kocmalova, et al.
Published: (2021-07-01)
Importance of age at diagnosis of pulmonary hypertension in children living at high altitude: Longitudinal follow‐up of 86 patients
by: Gabriel F. Diaz, et al.
Published: (2025-04-01)
by: Gabriel F. Diaz, et al.
Published: (2025-04-01)
Perivascular Innervation in the Nasal Mucosa and Clinical Findings in Patients with Allergic Rhinitis and Idiopathic Rhinitis
by: Thiago Carvalho, et al.
Published: (2023-10-01)
by: Thiago Carvalho, et al.
Published: (2023-10-01)
Large-Scale Profiling on lncRNAs in Human Platelets: Correlation with Platelet Reactivity
by: Yeying Sun, et al.
Published: (2022-07-01)
by: Yeying Sun, et al.
Published: (2022-07-01)
The protective role of muscone in the development of COPD
by: Tiantian Feng, et al.
Published: (2025-02-01)
by: Tiantian Feng, et al.
Published: (2025-02-01)
Evaluation of nigella sativa's cold press oil as vaccine adjuvant
by: Uçkun Sait Uçan, et al.
Published: (2020-10-01)
by: Uçkun Sait Uçan, et al.
Published: (2020-10-01)
Fluconazole worsened lung inflammation, partly through lung microbiome dysbiosis in mice with ovalbumin-induced asthma
by: Jesadakorn Worasilchai, et al.
Published: (2024-10-01)
by: Jesadakorn Worasilchai, et al.
Published: (2024-10-01)
Immunomodulatory Effects of Betaine on
Experimental Model of Asthma in Balb/c Mice
by: Zeinab Shakarami Gandabeh, et al.
Published: (2020-05-01)
by: Zeinab Shakarami Gandabeh, et al.
Published: (2020-05-01)
Bibliometric Analysis on the Central Regulation of Airway Allergic Hyperreactivity Diseases Based on Bibliometric Analysis: From Lung-Brain Axis to Nasal-Brain Axis
by: Shi X, et al.
Published: (2025-05-01)
by: Shi X, et al.
Published: (2025-05-01)
Acute airway eosinophilic inflammation model in mice induced by ovalbumin, house dust mite, or shrimp tropomyosin: a comparative study
by: Liangyu Xu, et al.
Published: (2025-06-01)
by: Liangyu Xu, et al.
Published: (2025-06-01)
Effects of Roflumilast, Selective PDE4 Inhibitor, on Airway Reactivity in Ovalbumin-Sensitized Guinea Pigs
by: Tharmalingam Nirmathan, et al.
Published: (2015-05-01)
by: Tharmalingam Nirmathan, et al.
Published: (2015-05-01)
Biomarkers of Airway Disease, Barrett’s and Underdiagnosed Reflux Noninvasively (BAD-BURN) in World Trade Center exposed firefighters: a case–control observational study protocol
by: Urooj Javed, et al.
Published: (2024-08-01)
by: Urooj Javed, et al.
Published: (2024-08-01)
Nasal Reactivity After Radiofrequency Ablation of Peripheral Branches of Posterior Nasal Nerve
by: Samy Elwany, et al.
Published: (2022-12-01)
by: Samy Elwany, et al.
Published: (2022-12-01)
The Lung Function Impairment in Non-Atopic Patients With Chronic Rhinosinusitis and Its Correlation Analysis
by: Linghao Zhang, et al.
Published: (2016-12-01)
by: Linghao Zhang, et al.
Published: (2016-12-01)
Apoptosis-resistant megakaryocytes produce large and hyperreactive platelets in response to radiation injury
by: Chang-Hong Du, et al.
Published: (2023-12-01)
by: Chang-Hong Du, et al.
Published: (2023-12-01)
Selective depletion of basophils ameliorates immunoglobulin E-mediated anaphylaxis
by: Takeshi Nakamura, et al.
Published: (2017-03-01)
by: Takeshi Nakamura, et al.
Published: (2017-03-01)
Monensin inhibits mast cell mediated airway contractions in human and guinea pig asthma models
by: Jielu Liu, et al.
Published: (2022-11-01)
by: Jielu Liu, et al.
Published: (2022-11-01)
Preparation, Characterization and Stability of Ovalbumin/Polysaccharide Nanocomplexes Loaded with Anthocyanins
by: MAO Shuifang, ZENG Yujun, TIAN Jinhu, YE Xingqian
Published: (2025-10-01)
by: MAO Shuifang, ZENG Yujun, TIAN Jinhu, YE Xingqian
Published: (2025-10-01)
Effects of Viola tricolor Flower Hydroethanolic Extract on Lung Inflammation in a Mouse Model of Chronic Asthma
by: Elham Harati, et al.
Published: (2018-10-01)
by: Elham Harati, et al.
Published: (2018-10-01)
Similar Items
-
Toll-like receptor activation induces airway obstruction and hyperresponsiveness in guinea pigs
by: Yujiao Xiang, et al.
Published: (2024-11-01) -
Prenatal Maternal Lipopolysaccharide and Mild Newborn Hyperoxia Increase Intrapulmonary Airway but Not Vessel Reactivity in a Mouse Model
by: Margaret E. Kuper-Sassé, et al.
Published: (2021-03-01) -
Pharmacological OGG1 inhibition decreases murine allergic airway inflammation
by: Lloyd Tanner, et al.
Published: (2022-10-01) -
Pharmacological inhibition of MutT homolog 1 (MTH1) in allergic airway inflammation as a novel treatment strategy
by: Anna Adler, et al.
Published: (2025-03-01) -
Zoledronic Acid Targeting of the Mevalonate Pathway Causes Reduced Cell Recruitment and Attenuates Pulmonary Fibrosis
by: Lloyd Tanner, et al.
Published: (2022-06-01)
