Dysregulated PI3K Signaling in B Cells of CVID Patients

The altered wiring of signaling pathways downstream of antigen receptors of T and B cells contributes to the dysregulation of the adaptive immune system, potentially causing immunodeficiency and autoimmunity. In humans, the investigation of such complex systems benefits from nature’s experiments in...

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Bibliographic Details
Published in:	Cells
Main Authors:	Ina Harder, Matthias Münchhalfen, Geoffroy Andrieux, Melanie Boerries, Bodo Grimbacher, Hermann Eibel, Maria Elena Maccari, Stephan Ehl, Jürgen Wienands, Julia Jellusova, Klaus Warnatz, Baerbel Keller
Format:	Article
Language:	English
Published:	MDPI AG 2022-01-01
Subjects:	CVID B cells immune dysregulation PI3K mTOR S6
Online Access:	https://www.mdpi.com/2073-4409/11/3/464

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