Improved intestinal absorption of paclitaxel by mixed micelles self-assembled from vitamin E succinate-based amphiphilic polymers and their transcellular transport mechanism and intracellular trafficking routes

To ensure that antitumor drugs can be effectively transported across intestinal barrier and then quickly released in tumor cells, mixed polymeric micelles (Mix-PMs) were designed and fabricated by combining poly(2-ethyl-2-oxazoline)-vitamin E succinate (PEOz-VES) with TPGS1000 for enhancing intestin...

وصف كامل

التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Drug Delivery
المؤلفون الرئيسيون:	Xiaoyou Qu, Yang Zou, Chuyu He, Yuanhang Zhou, Yao Jin, Yunqiang Deng, Ziqi Wang, Xinru Li, Yanxia Zhou, Yan Liu
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Taylor & Francis Group 2018-01-01
الموضوعات:	paclitaxel mixed polymeric micelles intestinal absorption intracellular trafficking transcytosis mechanism
الوصول للمادة أونلاين:	http://dx.doi.org/10.1080/10717544.2017.1419513