Effects of Hyperandrogenism in PCOS: A Review Analysis

• Published in: Pakistan Journal of Medical Research
• Main Author: javeria khan
• Format: Article
• Language: English
• Published: Health Research Institute (HRI), National Institute of Health (NIH) 2024-10-01
• Subjects: Ovulation; infertility; hyperandrogenism; hirsutism; phenotype
• Online Access: https://pjmr.org.pk/index.php/pjmr/article/view/432

The endocrine condition known as Poly Cystic Ovary Syndrome (PCOS) is becoming more common  in the local areas of Pakistan. Concerningly, the prevalence of PCOS among women who are fertile has been increasing. It plays a significant role in the worldwide population's infertility and subfertility. PCOS patients frequently exhibit a variety of symptoms, including ovarian cysts, hyperandrogenism, irregular menstruation, and ovulatory abnormalities. The symptoms are frequently misdiagnosed or disregarded, and they take longer to manifest. Due to PCOS's complex nature, its cause is yet unknown. Several scientific associations have developed diagnostic standards for PCOS and have identified three distinct phenotypes. The primary symptom of PCOS in all phenotypes is hyperandrogenism, or an excess of androgen production. This review focuses on hyperandrogenism and the several variables that cause hyperandrogenic states in Pakistani women with PCOS. Additionally, this review addresses and summarises new and prior research on the connection between hyperandrogenism and PC This review's objective is to evaluate the evidence-based relationship between hyperandrogenism and PCOS critically in Pakistan. The PRISMA flowchart approach was used to document the study selection process. The research from the last six years that exclusively addressed hyperandrogenism and PCOS met the inclusion criteria. Studies that do not concentrate on PCOS or hyperandrogenism are among the exclusion criteria. 34 of the first 50 studies that were found were included in the final evaluation following screening. Information was taken from Pakistani locals. Using qualitative methodologies, data was synthesised so that similar themes and patterns from several studies could be...........