Insights into protein aggregation by NMR characterization of insoluble SH3 mutants solubilized in salt-free water.

Protein aggregation in vivo has been extensively associated with a large spectrum of human diseases. On the other hand, mechanistic insights into protein aggregation in vitro were incomplete due to the inability in solubilizing insoluble proteins for high-resolution biophysical investigations. Howev...

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Bibliographic Details
Published in:	PLoS ONE
Main Authors:	Jingxian Liu, Jianxing Song
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2009-01-01
Online Access:	http://europepmc.org/articles/PMC2776303?pdf=render

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