Amphetamine Derivatives as Potent Central Nervous System Multitarget SERT/NET/H₃ Agents: Synthesis and Biological Evaluation

In this research, a variety of novel amphetamine derivatives were synthesized and assessed for their potential as multifaceted antidepressant agents. Among these compounds, compound <b>11b</b> demonstrated potent inhibitory effects on both serotonin and noradrenaline transporters (SERT/N...

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Bibliographic Details

Published in:	Molecules
Main Authors:	Quxiang Li, Lili Ren, Dongli Wang, Junyong Luo, Changda Xu, Jian Feng, Yufan Qiu, Xiangqing Xu, Guoguang Chen
Format:	Article
Language:	English
Published:	MDPI AG 2024-11-01
Subjects:	amphetamine multitarget antidepressant molecular docking
Online Access:	https://www.mdpi.com/1420-3049/29/22/5240