Messenger RNA expressing PfCSP induces functional, protective immune responses against malaria in mice
Abstract Human malaria affects the vast majority of the world’s population with the Plasmodium falciparum species causing the highest rates of morbidity and mortality. With no licensed vaccine and leading candidates achieving suboptimal protection in the field, the need for an effective immunoprophy...
| Published in: | npj Vaccines |
|---|---|
| Main Authors: | Katherine L. Mallory, Justin A. Taylor, Xiaoyan Zou, Ishita N. Waghela, Cosette G. Schneider, Michael Q. Sibilo, Neeraja M. Punde, Leah C. Perazzo, Tatyana Savransky, Martha Sedegah, Sheetij Dutta, Chris J. Janse, Norbert Pardi, Paulo J. C. Lin, Ying K. Tam, Drew Weissman, Evelina Angov |
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-06-01
|
| Online Access: | https://doi.org/10.1038/s41541-021-00345-0 |
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