Antibacterial Profile of a Microbicidal Agent Targeting Tyrosine Phosphatases and Redox Thiols, Novel Drug Targets

The activity profile of a protein tyrosine phosphatase (PTP) inhibitor and redox thiol oxidant, nitropropenyl benzodioxole (NPBD), was investigated across a broad range of bacterial species. In vitro assays assessed inhibitory and lethal activity patterns, the induction of drug variants on long term...

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Bibliographic Details

Published in:	Antibiotics
Main Authors:	Kylie White, Gina Nicoletti, Hugh Cornell
Format:	Article
Language:	English
Published:	MDPI AG 2021-10-01
Subjects:	antimicrobial nitropropenyl benzodioxole nitroalkenyl benzenes tyrosine signaling protein tyrosine phosphatase inhibitor thiol oxidant
Online Access:	https://www.mdpi.com/2079-6382/10/11/1310