Effects of polyunsaturated fatty acids on mitigation of the side effects of isotretionin treatment for patients with acne vulgaris: a narrative review

Acne vulgaris is one of the most common dermatological problems prompting the need for medical consultation. Currently, isotretinoin is recommended for the treatment of severe, refractory nodular acne or for prolonging remission of moderate to severe acne. Despite its high efficacy, it causes advers...

Full description

Bibliographic Details
Published in:	Family Medicine & Primary Care Review
Main Authors:	Agnieszka Kaźmierska, Izabela Anna Bolesławska, Juliusz Przysławski
Format:	Article
Language:	English
Published:	Termedia Publishing House 2024-12-01
Subjects:	unsaturated fatty acids acne vulgaris isotretinoin.
Online Access:	https://www.termedia.pl/Effects-of-polyunsaturated-fatty-acids-on-mitigation-of-the-side-effects-of-isotretionin-treatment-for-patients-with-acne-vulgaris-a-narrative-review,95,55125,1,1.html

Similar Items

A systematic review of isotretinoin dosing in acne vulgaris
by: Aoife U. Daly, et al.
Published: (2023-09-01)

Acne vulgaris - review on pathogenesis and treatment
by: Bartłomiej Żmuda, et al.
Published: (2024-01-01)

The effects of isotretinoin on the inner ear in patients with acne vulgaris
by: Esra İnan Doğan, et al.
Published: (2022-03-01)

Efficacy of Isotretinoin in The Management of Enlarged Facial Pores in Moderate and Severe Acne Vulgaris Patients
by: Waleed Gaber, et al.
Published: (2023-08-01)

Comparing the efficacy of low dose and conventional dose of oral isotretinoin in treatment of moderate and severe acne vulgaris
by: Gita Faghihi, et al.
Published: (2017-01-01)

Effect of Systemic Isotretinoin on serum Irisin level in Acne Vulgaris patients
by: Soheir Abdel-Hamid, et al.
Published: (2025-07-01)

Effect of oral isotretinoin therapy on thyroid function in patients with moderate-to-severe acne vulgaris: A prospective study
by: Fahad AlSaif, et al.
Published: (2020-01-01)

Circulating TWEAK levels in patients with acne vulgaris: Effect of oral isotretinoin therapy
by: Hassan M. Ibrahim, et al.
Published: (2024-06-01)

Efficacy of oral isotretinoin monotherapy compared to combination isotretinoin and topical clascoterone for severe acne vulgaris: a multi-center retrospective study
by: UYeong Choi, et al.
Published: (2025-12-01)

Evaluating the Role of Omega 3 on the Side Effects of Isotretinoin in Patients with the Acnea Vulgaris
by: Mina Mirnezami
Published: (2017-01-01)

Lactobacillus plantarum MH-301 as an effective adjuvant to isotretinoin in the treatment of acne vulgaris: a randomized and open-label trail
by: Lili Liang, et al.
Published: (2024-01-01)

Experiência de 65 anos no tratamento da acne e de 26 anos com isotretinoína oral A 65-year experience treating acne, including 26 years with oral isotretinoin
by: Sebastião de Almeida Prado Sampaio, et al.
Published: (2008-08-01)

The Effect of Isotretinoin on Insulin Resistance and Serum Adiponectin Levels in Acne Vulgaris Patients: A Systematic Review and Meta-Analysis
by: Eleni Paschalidou, et al.
Published: (2024-05-01)

Combination of chemical peels and oral isotretinoin in the treatment of acne scars
by: Marina Soares Silverio, et al.
Published: (2025-10-01)

Evaluation of the Effect of Oral Isotretinoin on the Level of Serum YKL40 in Acne Vulgaris Patients: A Cross-Sectional Case-Control
by: Ali MA, et al.
Published: (2023-11-01)

Difficulties in the treatment of acne fulminans – case report
by: Dorota Kozłowska, et al.
Published: (2015-06-01)

Development of acute sacroiliitis due to the use of oral isotretinoin in patients with acne vulgaris: Four case presentation
by: Özlem Karadağ Köse, et al.
Published: (2017-11-01)

Oral spironolactone for acne vulgaris in females: Evidence review and practical recommendations
by: Katina J. Selvaraj, BA, BSc, MD, MMed (Clin Epi), et al.
Published: (2025-09-01)

Serum lipid profile in adolescents and adults with acne vulgaris receiving isotretinoin
by: Kaveh Gharaei Nejad, et al.
Published: (2024-08-01)

Outcomes and Adverse Effects of Isotretinoin in Acne Treatment: A Systematic Review
by: Kinga Tylczyńska, et al.
Published: (2024-11-01)

Facial hypertrichosis after isotretinoin therapy: Is it a side effect or coincidence?
by: Esra Saraç, et al.
Published: (2022-03-01)

Factors Aggravating or Precipating Acne
by: Kairavee Dave, et al.
Published: (2010-06-01)

Efficacy of Topical 0.05% Isotretinoin Gel Versus 0.1% Adapalene Gel in The Treatment of Mild to Moderate Acne Vulgaris
by: Summaya Saleem, et al.
Published: (2023-02-01)

Exploring the Incidence and Risk Factors of Dyslipidemia in Patients with Severe Acne Vulgaris on Systemic Isotretinoin Therapy: Findings from a Prospective Study
by: Jihan Muhaidat, et al.
Published: (2025-02-01)

Markers of Oxidative Stress in Patients with Acne: A Literature Review
by: Gabriela Loredana Popa, et al.
Published: (2023-06-01)

A common but not well-known cause in anal fissure development and treatment failure: Isotretinoin treatment for acne vulgaris
by: Pelin Basim, et al.
Published: (2020-12-01)

Efficacy of Combined Oral Isotretinoin and Desloratadine or Levocetirizine vs. Isotretinoin Monotherapy in Treating Acne Vulgaris: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
by: Julia Woźna, et al.
Published: (2025-07-01)

Integrated plasma metabolomic and proteomic analysis uncover the effects and mechanisms of isotretinoin in severe acne
by: Manqi Xia, et al.
Published: (2025-08-01)

Levels of several inflammatory cytokines in acne patients before and after isotretinoin therapy: a randomized, controlled clinical trial
by: Wanling Qi, et al.
Published: (2025-12-01)

Acne Vulgaris Management: A Review of First-Line and Advanced Pharmacological Treatments
by: Krzysztof Dobrzeniecki, et al.
Published: (2025-02-01)

Topical, Biological and Clinical Challenges in the Management of Patients with Acne Vulgaris
by: Anwar Al-Hammadi, et al.
Published: (2016-05-01)

Oral isotretinoin for acne vulgaris side effects on the ocular surface: Hyaluronic acid and galacto-xyloglucan as treatment for dry eye disease signs and symptoms
by: María Carmen Sánchez-González, et al.
Published: (2022-07-01)

The Effect of Oral Isotretinoin Therapy on Meibomian Gland Characteristics in Patients with Acne Vulgaris
by: Aleksandra Zakrzewska, et al.
Published: (2023-06-01)

Untargeted Lipidomics Analysis to Discover Lipid Profiles and Biomarkers of Rabbit Acne Model and Reveal Action Mechanism of Isotretinoin
by: Wu L, et al.
Published: (2024-09-01)

Acne vulgaris in a 22‐year‐old cystic fibrosis patient treated with Elexacaftor‐Tezacaftor‐Ivacaftor and good clinical response to isotretinoin—A case report
by: Isabelle Pfeiffer, et al.
Published: (2024-12-01)

Drugs and other substances aggravating acne vulgaris
by: Karolina Zalewa, et al.
Published: (2024-10-01)

Evaluation of the Incidence of Anal Fissures in Patients Who Systemic Isotretinoin Therapy for Acne
by: Hamza Aktaş, et al.
Published: (2023-07-01)

Effects of Oral Isotretinoin Therapy on Nasal Dryness and Nasal Obstruction in Patients with Acne Vulgaris: Objective and Subjective Assessments Based on the Dose and Duration of Therapy
by: Enes Yiğit, et al.
Published: (2022-02-01)

The role of diet in development of acne vulgaris
by: Mateusz Pawlicki, et al.
Published: (2019-08-01)

To the question of the effect of isotretinoin on the neuropsychic state of patients with acne
by: Alexey V. Samtsov
Published: (2023-07-01)