Transcription factors in fibroblast plasticity and CAF heterogeneity

Abstract In recent years, research focused on the multifaceted landscape and functions of cancer-associated fibroblasts (CAFs) aimed to reveal their heterogeneity and identify commonalities across diverse tumors for more effective therapeutic targeting of pro-tumoral stromal microenvironment. Howeve...

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Bibliographic Details
Published in:	Journal of Experimental & Clinical Cancer Research
Main Authors:	Roberta Melchionna, Paola Trono, Anna Di Carlo, Francesca Di Modugno, Paola Nisticò
Format:	Article
Language:	English
Published:	BMC 2023-12-01
Subjects:	Cancer Associated fibroblasts (CAFs) Transcription factors (TFs) CAF activation CAF subtypes Fibrosis
Online Access:	https://doi.org/10.1186/s13046-023-02934-4

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