Infant Botulism, Israel, 2007–2021

• الحاوية / القاعدة: Emerging Infectious Diseases
• المؤلفون الرئيسيون: Bar Goldberg, Dana Danino, Yoel Levinsky, Itzhak Levy, Rachel Straussberg, Halima Dabaja-Younis, Alex Guri, Yotam Almagor, Diana Tasher, Daniel Elad, Zina Baider, Shlomo Blum, Oded Scheuerman
• التنسيق: مقال
• اللغة: الإنجليزية
• منشور في: Centers for Disease Control and Prevention 2023-02-01
• الموضوعات: infant botulism; pediatrics; epidemiology; honey; botulism neurotoxin; Clostridium botulinum
• الوصول للمادة أونلاين: https://wwwnc.cdc.gov/eid/article/29/2/22-0991_article
• تدمد: 1080-6040; 1080-6059

Infant botulism (IB) is an intestinal toxemia that manifests as descending paralysis, constipation, and, in some cases, respiratory failure. Laboratory-confirmed IB cases are rare, and recent data in Israel are lacking. We conducted a national multicenter retrospective study of laboratory-confirmed IB cases reported in Israel during 2007–2021. A total of 8 cases were reported during the study period. During 2019–2021, incidence may have increased because of a cluster of 5 cases. Infant median age for diagnosis was 6.5 months, older than previously reported (3 months). Most cases occurred during March–July. Honey consumption was reported in 1 case, and possible environmental risk factors (living nearby rural or construction areas, dust exposure, and having a father who works as a farmer) were reported in 6 cases. Although IB is rare, its incidence in Israel may have increased over recent years, and its epidemiology and risk factors differ from cases reported previously in Israel.