Panaxatriol saponins exert anti-renal fibrosis by suppressing TNF-α mediated inflammation and TGF-β1/Smad3 signaling pathway

Renal fibrosis is a key pathological process in the progression of chronic kidney disease (CKD). Panaxatriol saponins (PTS), the main bioactive compounds extracted from Panax notoginseng (Burk.) F.H. Chen, have demonstrated antioxidative and anti-inflammatory activities. This study aimed to investig...

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Bibliographic Details
Published in:	Renal Failure
Main Authors:	Si Yi, Feiyan Li, Xin Ma, Yao Xu, Weijing Lai, Hongxi Chen, Junming Fan, Nan Mao, Sichong Ren
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2025-12-01
Subjects:	Panaxatriol saponins chronic kidney disease renal fibrosis TNF-α TGF-β1/smad3 UUO model
Online Access:	https://www.tandfonline.com/doi/10.1080/0886022X.2025.2516774

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