SETD2 mutations in primary central nervous system tumors

Abstract Mutations in SETD2 are found in many tumors, including central nervous system (CNS) tumors. Previous work has shown these mutations occur specifically in high grade gliomas of the cerebral hemispheres in pediatric and young adult patients. We investigated SETD2 mutations in a cohort of appr...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:	Acta Neuropathologica Communications
المؤلفون الرئيسيون:	Angela N. Viaene, Mariarita Santi, Jason Rosenbaum, Marilyn M. Li, Lea F. Surrey, MacLean P. Nasrallah
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	BMC 2018-11-01
الموضوعات:	SETD2 Histone Brain tumor Glioma Epigenetics H3K36me3
الوصول للمادة أونلاين:	http://link.springer.com/article/10.1186/s40478-018-0623-0

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