Inhibitory effect and mechanism of alkaloids derived from Gelsemium elegans Benth on lung cancer
Objective To determine the anti-lung cancer effect of koumine (KOU) and total alkaloids of Gelsemium elegans Benth (TAG) and investigate the underlying mechanism. Methods After low, medium and high concentrations (100, 150, 200 μg/mL) of KOU were used to treat human lung adenocarcinoma cell lines A5...
| Published in: | 陆军军医大学学报 |
|---|---|
| Main Authors: | JIN Mingjing, LI Yanping, ZHOU Huansi |
| Format: | Article |
| Language: | Chinese |
| Published: |
Editorial Office of Journal of Army Medical University
2024-12-01
|
| Subjects: | |
| Online Access: | https://aammt.tmmu.edu.cn/html/202403114.htm |
Similar Items
<i>Gelsemium elegans</i> Benth: Chemical Components, Pharmacological Effects, and Toxicity Mechanisms
by: Hailing Lin, et al.
Published: (2021-11-01)
by: Hailing Lin, et al.
Published: (2021-11-01)
Analgesic monoterpene indole alkaloids from Gelsemium elegans stems
by: Pengfei JIN, et al.
Published: (2022-09-01)
by: Pengfei JIN, et al.
Published: (2022-09-01)
The complete mitochondrial genome of heartbreak grass Gelsemium elegans (Gardner & Champ.) Benth. (Gelsemiaceae)
by: Yong-Hui Jin, et al.
Published: (2019-07-01)
by: Yong-Hui Jin, et al.
Published: (2019-07-01)
Integration of Metabolomics and Transcriptomicsto Comprehensively Evaluate the Metabolic Effects of <i>Gelsemium elegans</i> on Pigs
by: Chong-Yin Huang, et al.
Published: (2021-04-01)
by: Chong-Yin Huang, et al.
Published: (2021-04-01)
The toxic components, toxicological mechanism and effective antidote for Gelsemium elegans poisoning
by: Niping Li, et al.
Published: (2025-09-01)
by: Niping Li, et al.
Published: (2025-09-01)
Complete sequence and comparative analysis of the chloroplast genome of Gelsemium elegans
by: Zhenlu Wang, et al.
Published: (2019-01-01)
by: Zhenlu Wang, et al.
Published: (2019-01-01)
New Monoterpenoid Indoles with Osteoclast Activities from <i>Gelsemium elegans</i>
by: Xin Wei, et al.
Published: (2021-12-01)
by: Xin Wei, et al.
Published: (2021-12-01)
Sex Differences in the In Vivo Exposure Process of Multiple Components of <i>Gelsemium elegans</i> in Rats
by: Meng-Ting Zuo, et al.
Published: (2022-12-01)
by: Meng-Ting Zuo, et al.
Published: (2022-12-01)
The toxicology and detoxification of Gelsemium: Traditional and modern views
by: Chong-Yin Huang, et al.
Published: (2024-09-01)
by: Chong-Yin Huang, et al.
Published: (2024-09-01)
Caution on the severe damage of Gelsemium elegans poisoning: a case report on family poisoning and systematic review
by: Yawen Zhao, et al.
Published: (2025-08-01)
by: Yawen Zhao, et al.
Published: (2025-08-01)
Structural Elucidation and Cytotoxic Activity of New Monoterpenoid Indoles from <i>Gelsemium elegans</i>
by: Da Song, et al.
Published: (2023-03-01)
by: Da Song, et al.
Published: (2023-03-01)
Molecular identification and functional characterization of a transcription factor GeRAV1 from Gelsemium elegans
by: Tianzhen Cui, et al.
Published: (2024-01-01)
by: Tianzhen Cui, et al.
Published: (2024-01-01)
Excretion, Metabolism, and Tissue Distribution of <i>Gelsemium elegans</i> (<i>Gardn. & Champ.</i>) <i>Benth</i> in Pigs
by: Xiao Ma, et al.
Published: (2022-04-01)
by: Xiao Ma, et al.
Published: (2022-04-01)
The multicomponent residue depletion of Gelsemium elegans in pig tissues, urine, and plasma
by: Yong Wu, et al.
Published: (2023-01-01)
by: Yong Wu, et al.
Published: (2023-01-01)
Internal reference genes for normalizing quantitative real-time PCR in different tissues of Gelsemium elegans or under low temperature, MeJA, and SA stresses
by: Chuihuai You, et al.
Published: (2024-01-01)
by: Chuihuai You, et al.
Published: (2024-01-01)
Two-Dimensional Liquid Chromatography Method for the Determination of <i>Gelsemium</i> Alkaloids in Honey
by: Xiao Ma, et al.
Published: (2022-09-01)
by: Xiao Ma, et al.
Published: (2022-09-01)
The antianxiety effects of koumine and gelsemine, two main active components in the traditional Chinese herbal medicine Gelsemium: A comprehensive review
by: Jiangyu Long, et al.
Published: (2023-12-01)
by: Jiangyu Long, et al.
Published: (2023-12-01)
Antianxiety Activity of Methanol Extract of Gelsemium sempervirens (Linn.) Ait.
by: Garg Vandana, et al.
Published: (2012-05-01)
by: Garg Vandana, et al.
Published: (2012-05-01)
Determination of content of indole alkaloids in cell biomass of Rauwolfia serpentina Benth. ex Kurz tissue culture
by: O. A. Bieda, et al.
Published: (2021-03-01)
by: O. A. Bieda, et al.
Published: (2021-03-01)
<i>In Situ</i> Visual Distribution of Gelsemine, Koumine, and Gelsenicine by MSI in <i>Gelsemium</i><i>elegans</i> at Different Growth Stages
by: Zi-Han Wu, et al.
Published: (2022-03-01)
by: Zi-Han Wu, et al.
Published: (2022-03-01)
Secondary metabolites, antibacterial and antioxidant properties of the leaf extracts of Acacia rigidula benth. and Acacia berlandieri benth.
by: Peter Cavazos, et al.
Published: (2021-04-01)
by: Peter Cavazos, et al.
Published: (2021-04-01)
C. elegans-based screen identifies lysosome-damaging alkaloids that induce STAT3-dependent lysosomal cell death
by: Yang Li, et al.
Published: (2018-04-01)
by: Yang Li, et al.
Published: (2018-04-01)
High diluted molecules and gene expression
by: Salvatore eChirumbolo
Published: (2014-08-01)
by: Salvatore eChirumbolo
Published: (2014-08-01)
The complete chloroplast genome sequence of Ventilago leiocarpa Benth
by: Xiang Lu, et al.
Published: (2021-03-01)
by: Xiang Lu, et al.
Published: (2021-03-01)
Oxidative biotransformation of stemofoline alkaloids
by: Manlika Phaya, et al.
Published: (2021-01-01)
by: Manlika Phaya, et al.
Published: (2021-01-01)
In Vitro Antioxidant and Anti-Neuroinflammatory Effects of <i>Elsholtzia blanda</i> (Benth.) Benth.
by: Yeo Dae Yoon, et al.
Published: (2025-06-01)
by: Yeo Dae Yoon, et al.
Published: (2025-06-01)
SMRT sequencing of full-length transcriptome and gene expression analysis in two chemical types of Pogostemon cablin (Blanco) Benth.
by: Hongyi Zhang, et al.
Published: (2022-02-01)
by: Hongyi Zhang, et al.
Published: (2022-02-01)
HEPATOPROTECTIVE ACIVITY OF THE ETHANOLIC EXTRACT OF DOG FRUIT RIND (Pithecellobium lobatum Benth.)
by: Ruqiah Ganda Putri Panjaitan, et al.
Published: (2017-11-01)
by: Ruqiah Ganda Putri Panjaitan, et al.
Published: (2017-11-01)
Alkaloids extracted from Dendrobium officinale grown in diverse environments exhibited robust antioxidative and antiaging activity
by: Yichen Liu, et al.
Published: (2025-11-01)
by: Yichen Liu, et al.
Published: (2025-11-01)
Integrated physiological, biochemical and transcriptomic analyses elucidate the response of alpine plant Lamiophlomis rotata (Benth.) Kudo to Low-Nitrogen stress
by: Liwen Zhong, et al.
Published: (2025-07-01)
by: Liwen Zhong, et al.
Published: (2025-07-01)
The complete chloroplast genome of Angelonia angustifolia Benth. (Plantaginaceae), an ornamental and medicinal plant
by: Jianhua Yue, et al.
Published: (2022-12-01)
by: Jianhua Yue, et al.
Published: (2022-12-01)
Hsian-Tsao (Mesona chinensis Benth.) Extract Improves the Thermal Tolerance of Drosophila melanogaster
by: Yan Huang, et al.
Published: (2022-05-01)
by: Yan Huang, et al.
Published: (2022-05-01)
Nephroprotective Effect of the Leaf Extract of Ajuga remota Benth Against Gentamicin-Induced Nephrotoxicity in Swiss Albino Mice
by: Akinaw MA, et al.
Published: (2024-03-01)
by: Akinaw MA, et al.
Published: (2024-03-01)
QUANTITATIVE DETERMINATION OF THE AMOUNT OF FLAVONOIDS IN THE HERB OF SALVIA FARINACEA BENTH.
by: O. I. Popova, et al.
Published: (2016-03-01)
by: O. I. Popova, et al.
Published: (2016-03-01)
Complete chloroplast genome sequence of Pithecellobium clypearia (Jack) Benth.
by: Ying-hua Wang, et al.
Published: (2022-05-01)
by: Ying-hua Wang, et al.
Published: (2022-05-01)
Transcriptome Analysis Reveals Fruit Quality Formation in <i>Actinidia eriantha</i> Benth
by: Peiyu Wang, et al.
Published: (2023-12-01)
by: Peiyu Wang, et al.
Published: (2023-12-01)
The Antioxidant and Hypolipidemic Effects of <i>Mesona Chinensis Benth</i> Extracts
by: Luhua Xiao, et al.
Published: (2022-05-01)
by: Luhua Xiao, et al.
Published: (2022-05-01)
The genus Piptadenia Benth.: pollen morphology and taxonomic implications
by: Ana Flávia Trabuco Duarte, et al.
Published: (2025-05-01)
by: Ana Flávia Trabuco Duarte, et al.
Published: (2025-05-01)
Sunscreen Lotion of Miana Leaves (Coleus atropurpureus Benth)
by: Rolan Rusli, et al.
Published: (2019-06-01)
by: Rolan Rusli, et al.
Published: (2019-06-01)
Therapeutic Role of Alkaloids and Alkaloid Derivatives in Cancer Management
by: Kolawole Olofinsan, et al.
Published: (2023-07-01)
by: Kolawole Olofinsan, et al.
Published: (2023-07-01)
Similar Items
-
<i>Gelsemium elegans</i> Benth: Chemical Components, Pharmacological Effects, and Toxicity Mechanisms
by: Hailing Lin, et al.
Published: (2021-11-01) -
Analgesic monoterpene indole alkaloids from Gelsemium elegans stems
by: Pengfei JIN, et al.
Published: (2022-09-01) -
The complete mitochondrial genome of heartbreak grass Gelsemium elegans (Gardner & Champ.) Benth. (Gelsemiaceae)
by: Yong-Hui Jin, et al.
Published: (2019-07-01) -
Integration of Metabolomics and Transcriptomicsto Comprehensively Evaluate the Metabolic Effects of <i>Gelsemium elegans</i> on Pigs
by: Chong-Yin Huang, et al.
Published: (2021-04-01) -
The toxic components, toxicological mechanism and effective antidote for Gelsemium elegans poisoning
by: Niping Li, et al.
Published: (2025-09-01)
