Towards interpretable speech biomarkers: exploring MFCCs

Abstract While speech biomarkers of disease have attracted increased interest in recent years, a challenge is that features derived from signal processing or machine learning approaches may lack clinical interpretability. As an example, Mel frequency cepstral coefficients (MFCCs) have been identifie...

Full description

Bibliographic Details
Published in:	Scientific Reports
Main Authors:	Brian Tracey, Dmitri Volfson, James Glass, R’mani Haulcy, Melissa Kostrzebski, Jamie Adams, Tairmae Kangarloo, Amy Brodtmann, E. Ray Dorsey, Adam Vogel
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-12-01
Online Access:	https://doi.org/10.1038/s41598-023-49352-2

Similar Items

Classifying Alzheimer's Disease Using Audio and Text-Based Representations of Speech
by: R'mani Haulcy, et al.
Published: (2021-01-01)

Utilizing MFCCs and TEO-MFCCs to Classify Stress in Females Using SSNNA
by: Nur Aishah Zainal, et al.
Published: (2025-01-01)

Integration of MFCCs and CNN for Multi-Class Stress Speech Classification on Unscripted Dataset
by: Nur Aishah Zainal, et al.
Published: (2024-07-01)

Computing nasalance with MFCCs and Convolutional Neural Networks.
by: Andrés Lozano, et al.
Published: (2024-01-01)

Extraction of Novel Features Based on Histograms of MFCCs Used in Emotion Classification from Generated Original Speech Dataset
by: Muhammet Pakyurek, et al.
Published: (2020-02-01)

Wearable Sensor-Based Assessments for Remotely Screening Early-Stage Parkinson’s Disease
by: Shane Johnson, et al.
Published: (2024-08-01)

Using a smartwatch and smartphone to assess early Parkinson’s disease in the WATCH-PD study over 12 months
by: Jamie L. Adams, et al.
Published: (2024-06-01)

The Recognition of Holy Qur’an Reciters Using the MFCCs’ Technique and Deep Learning
by: Ghassan Samara, et al.
Published: (2023-01-01)

Improved measurement of disease progression in people living with early Parkinson’s disease using digital health technologies
by: Matthew D. Czech, et al.
Published: (2024-03-01)

Acceptability of digital health technologies in early Parkinson's disease: lessons from WATCH-PD
by: T. Kangarloo, et al.
Published: (2024-08-01)

Using a smartwatch and smartphone to assess early Parkinson’s disease in the WATCH-PD study
by: Jamie L. Adams, et al.
Published: (2023-04-01)

Exploring Emotion and Emotional Variability as DigitalBiomarkers in Frontotemporal Dementia Speech
by: Yishu Gong, et al.
Published: (2024-01-01)

RTAIAED: A Real-Time Ambulance in an Emergency Detector with a Pyramidal Part-Based Model Composed of MFCCs and YOLOv8
by: Alessandro Mecocci, et al.
Published: (2024-04-01)

Digital assessment of speech in Huntington disease
by: Adonay S. Nunes, et al.
Published: (2024-01-01)

Central precocious puberty in Boston boys: A 10-year single center experience.
by: Lisa Swartz Topor, et al.
Published: (2018-01-01)

Metadata Framework to Support Deployment of Digital Health Technologies in Clinical Trials in Parkinson’s Disease
by: Derek L. Hill, et al.
Published: (2022-03-01)

The impact of interpreting students’ gestures and speech content on speech fluency of consecutive interpreting
by: Qiuya Zhang, et al.
Published: (2025-05-01)

Speech Genres and Interpretation of the Qur’an
by: Devin J. Stewart
Published: (2021-07-01)

Speech translation vs. Interpreting
by: Ildikó Horváth
Published: (2021-11-01)

Interpretable Probabilistic Identification of Depression in Speech
by: Stavros Ntalampiras
Published: (2025-02-01)

3092 Heidenhain variant sporadic Creutzfeld-Jakob disease with pre-symptomatic imaging changes and heterozygosity at codon 129
by: Amy Brodtmann, et al.
Published: (2024-08-01)

Interpreting the Manner of Speech in courts: an overlooked aspect
by: Ran Yi, et al.
Published: (2023-12-01)

The Reflexive Mode of Interpretation of Canonical Speech Situation
by: L U Tarieva
Published: (2013-12-01)

Ideological Shift in Interpreted Parliamentary Speeches: The Conference Interpreter as Meaning Co-Constructor
by: Dobkiewicz Patryk
Published: (2023-01-01)

Nouns, Verbs and Other Parts of Speech in Translation and Interpreting: Evidence from English Speeches Made in the European Parliament and Their German Translations and Interpretations
by: Volker Gast, et al.
Published: (2023-01-01)

THE ROLE OF GESTURES IN SHAPING THE INTERPRETATION OF SPEECH ACTS IN COMICS
by: Mutiara Pratama Putri, et al.
Published: (2024-07-01)

In-silico patterning of vascular mesenchymal cells in three dimensions.
by: Tal Danino, et al.
Published: (2011-01-01)

Speech Disfluencies in Consecutive Interpreting by Student Interpreters: The Role of Language Proficiency, Working Memory, and Anxiety
by: Nan Zhao
Published: (2022-05-01)

Trumpslation Analysed: Constraints and Interpreter Strategies in the Simultaneous Interpretation of Donald Trump’s Unscripted Speeches into Arabic
by: هبة المصري
Published: (2022-07-01)

Understanding hate speech: the HateInsights dataset and model interpretability
by: Muhammad Umair Arshad, et al.
Published: (2024-10-01)

The Pavlovian interpretation of speech and aphasia: Alexander Luria and Wilder Penfield
by: Richard Leblanc
Published: (2024-07-01)

Oral and written speech interpretation in sustainable development of ecological education
by: Moysova Olga, et al.
Published: (2023-01-01)

Advanced grad-CAM extensions for interpretable aphasia speech keyword classification: Bridging the gap in impaired speech with XAI
by: Gowri Prasood Usha, et al.
Published: (2024-12-01)

A novel, wearable, in-ear EEG technology to assess sleep and daytime sleepiness
by: Jonathan Berent, et al.
Published: (2026-05-01)

Exercise of Civil-Law Rights: Categories in the Context of Their Digitalization
by: V. L. Volfson
Published: (2021-10-01)

Integrity and Singularity: on a Civil Law Protection of the Privacy in the Countries of the Eurasian Economic Union
by: V. L. Volfson
Published: (2023-07-01)

Detecting Parkinson Disease Using a Web-Based Speech Task: Observational Study
by: Wasifur Rahman, et al.
Published: (2021-10-01)

Mapping Relevance of Digital Measures to Meaningful Symptoms and Impacts in Early Parkinson’s Disease
by: Jennifer R. Mammen, et al.
Published: (2023-06-01)

LINGUISTIC AND ACOUSTIC RESOURCES OF THE COMPUTER-BASED SYSTEM FOR ANALYSIS AND INTERPRETATION OF SPEECH INTONATION
by: Yu. A. Zdaranok
Published: (2018-02-01)

Speech Features of a Character as a Means of Interpreting a Literary Image
by: Abdukadyrova Tumisha, et al.
Published: (2024-01-01)