Isolation of Lytic Bacteriophages of <i>Escherichia coli</i> and Their Combined Use with Antibiotics Against the Causative Agents of Colibacillosis in Calves

The spread of antibiotic-resistant pathogenic <i>Escherichia coli</i> poses a serious threat to calf health on livestock farms. With the decline in antibiotic therapy effectiveness, alternative approaches such as phage therapy are urgently needed. This study aimed to isolate lytic <i&...

Full description

Bibliographic Details
Published in:	Veterinary Sciences
Main Authors:	Pavel G. Alexyuk, Andrey P. Bogoyavlenskiy, Kuralay S. Akanova, Yergali S. Moldakhanov, Timur T. Kerimov, Nadezhda S. Sokolova, Vladimir E. Berezin, Madina S. Alexyuk
Format:	Article
Language:	English
Published:	MDPI AG 2025-08-01
Subjects:	colibacillosis bacteriophage <i>Escherichia coli</i> antibiotic resistance phage therapy synergy
Online Access:	https://www.mdpi.com/2306-7381/12/9/817

Similar Items

Isolation and Characterization of Jumbo Coliphage vB_EcoM_Lh1B as a Promising Therapeutic Agent against Chicken Colibacillosis
by: Pavel Alexyuk, et al.
Published: (2023-06-01)

Genomic and Drug Resistance Profile of Bovine Multidrug-Resistant <i>Escherichia coli</i> Isolated in Kazakhstan
by: Pavel G. Alexyuk, et al.
Published: (2025-01-01)

Isolation and Characterization of Lytic Bacteriophages Active against Clinical Strains of <i>E. coli</i> and Development of a Phage Antimicrobial Cocktail
by: Pavel Alexyuk, et al.
Published: (2022-10-01)

Draft genome sequencing and in vitro activity data of the lytic vB_EcoM_AMO3598 bacteriophage effective against multi - drug resistant E. coliNCBI/GeneBank
by: Madina Alexyuk, et al.
Published: (2025-10-01)

Comparative analysis of immune responses to intraperitoneal administration of lytic E. coli bacteriophages in mice
by: Madina S. Alexyuk, et al.
Published: (2025-09-01)

Draft genome sequence data of methicillin-resistant Staphylococcus aureus, strain 4233
by: Madina Alexyuk, et al.
Published: (2024-06-01)

The Elicitation of an Antigen-Specific Antibody Immune Response Using a Nanoparticulate Adjuvant Derived from <i>Saponaria officinalis</i>
by: Andrey Bogoyavlenskiy, et al.
Published: (2025-08-01)

Evaluation of phage cocktail efficacy for controlling infections caused by pathogenic Escherichia coli in in vivo experiments
by: Alexyuk Madina, et al.
Published: (2024-01-01)

Draft genome sequences data of Mammaliicoccus lentus isolated from horse farm soil
by: Pavel Alexyuk, et al.
Published: (2023-12-01)

Immunization of pregnant cows with (coligen) to prevent colibacillosis in calves
by: K. O.AL-Jiburi ‎, et al.
Published: (1986-12-01)

Epipelagic microbiome of the Small Aral Sea: Metagenomic structure and ecological diversity
by: Madina Alexyuk, et al.
Published: (2021-02-01)

Swine Colibacillosis: Analysis of the Gut Bacterial Microbiome
by: Wanli Sha, et al.
Published: (2024-06-01)

Bacteriophage efficacy in controlling swine enteric colibacillosis pathogens: An in vitro study
by: Techaphon Songphasuk, et al.
Published: (2022-12-01)

Molecular and Serological Characteristics of Avian Pathogenic <i>Escherichia coli</i> Isolated from Various Clinical Cases of Poultry Colibacillosis in Poland
by: Jarosław Wilczyński, et al.
Published: (2022-04-01)

In-Feed vs. In-Water Chlortetracycline Administration on the Fecal Prevalence of Virulence Genes and Pathotypes of <i>Escherichia coli</i> Involved in Enteric Colibacillosis in Piglets
by: Ramya Kalam, et al.
Published: (2025-05-01)

Swine Colibacillosis: Global Epidemiologic and Antimicrobial Scenario
by: Maria Margarida Barros, et al.
Published: (2023-03-01)

<i>Gallic</i>, <i>Aconitic</i>, and <i>Crocetin</i> Acids as Potential TNF Modulators: An Integrated Study Combining Molecular Docking, Dynamics Simulations, ADMET Profiling, and Gene Expression Analysis
by: Adolat Manakbayeva, et al.
Published: (2025-07-01)

Determinants of Antibiotic Resistance and Virulence Factors in the Genome of <i>Escherichia coli</i> APEC 36 Strain Isolated from a Broiler Chicken with Generalized Colibacillosis
by: Dmitry S. Karpov, et al.
Published: (2024-10-01)

Case Study: Colibacillosis and Coccidiosis in Broiler Chicken Farm
by: Tyagita Tyagita Hartady, et al.
Published: (2024-12-01)

Serogrouping and Molecular Characterization of ESBL-Producing Avian Pathogenic <i>Escherichia coli</i> from Broilers and Turkeys with Colibacillosis in Algeria
by: Nadia Safia Chenouf, et al.
Published: (2025-03-01)

Draft genome sequences data of two Rosemountvirus phages isolated from soil near poultry farm
by: A. Bogoyavlenskiy, et al.
Published: (2022-08-01)

The Ability of Combined Flavonol and Trihydroxyorganic Acid to Suppress SARS-CoV-2 Reproduction
by: Andrey Bogoyavlenskiy, et al.
Published: (2024-12-01)

Swine enteric colibacillosis: diagnosis, therapy and antimicrobial resistance
by: Andrea Luppi
Published: (2017-08-01)

A systematic review on the role of biosecurity to prevent or control colibacillosis in broiler production
by: G. Tilli, et al.
Published: (2024-08-01)

Colibacillosis in a New Zealand white rabbit (Oryctolagus cuniculus)
by: Melissa Saravia, et al.
Published: (2017-02-01)

Characterization of tetA gene of Escherichia coli isolated from colibacillosis affected calves in Rangpur, Bangladesh
by: Jakiul Hasan Jihad, et al.
Published: (2024-03-01)

An Assessment of the Level of Protection Against Colibacillosis Conferred by Several Autogenous and/or Commercial Vaccination Programs in Conventional Pullets upon Experimental Challenge
by: Dimitris Koutsianos, et al.
Published: (2020-06-01)

In ovo administration of a phage cocktail partially prevents colibacillosis in chicks
by: Marianne Nicolas, et al.
Published: (2023-11-01)

Efficacy of Phage Therapy in Controlling Rabbit Colibacillosis and Changes in Cecal Microbiota
by: Jian Zhao, et al.
Published: (2017-05-01)

Draft Genome Sequence Data of <i>Streptomyces anulatus</i>, Strain K-31
by: Andrey P. Bogoyavlenskiy, et al.
Published: (2023-08-01)

Enrofloxacin Dose Optimization for the Treatment of Colibacillosis in Broiler Chickens Using a Drinking Behaviour Pharmacokinetic Model
by: Robin Temmerman, et al.
Published: (2021-05-01)

Virulence gene profiles of avian pathogenic <i>Escherichia coli</i> isolated from chickens with colibacillosis in Bulawayo, Zimbabwe
by: Joshua Mbanga, et al.
Published: (2015-04-01)

Prevalence of colibacillosis in chickens in greater Mymensingh district of Bangladesh
by: Md. Abdul Matin, et al.
Published: (2017-01-01)

Xiaochaihu Decoction Treatment of Chicken Colibacillosis by Improving Pulmonary Inflammation and Systemic Inflammation
by: Ke Song, et al.
Published: (2022-12-01)

Comparative Study on the Predominance of Lactobacillus spp. and Escherichia Coli in Healthy vs Colibacillosis Diseased Broilers
by: N Khalid, et al.
Published: (2023-07-01)

Characterizing avian pathogenic Escherichia coli (APEC) from colibacillosis cases, 2018
by: Darby M. Newman, et al.
Published: (2021-03-01)

Molecules produced by probiotics prevent enteric colibacillosis in pigs
by: Ricardo Nordeste, et al.
Published: (2017-11-01)

Distribution of serotypes and molecular characterization of avian pathogenic Escherichia coli isolated from chicken died of colibacillosis
by: T K RAJKHOWA, et al.
Published: (2021-04-01)

Evaluation of Lactobacilli and active dry yeast in the prevention and control of quail colibacillosis
by: A. S. E. D. Metwali, et al.
Published: (2007-06-01)

A study on subcutaneous infection model of colibacillosis in broilers: Selected immunological and hematological aspects
by: Z. Ghahramani, et al.
Published: (2024-12-01)