High-resolution DNA methylation screening of the major histocompatibility complex in multiple sclerosis

BackgroundThe HLA-DRB1 gene in the major histocompatibility complex (MHC) region in chromosome 6p21 is the strongest genetic factor identified as influencing multiple sclerosis (MS) susceptibility. DNA methylation changes associated with MS have been consistently detected at the MHC region. However,...

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Bibliographic Details
Published in:	Frontiers in Neurology
Main Authors:	Qin Ma, Danillo G. Augusto, Gonzalo Montero-Martin, Stacy J. Caillier, Kazutoyo Osoegawa, Bruce A. C. Cree, Stephen L. Hauser, Alessandro Didonna, Jill A. Hollenbach, Paul J. Norman, Marcelo Fernandez-Vina, Jorge R. Oksenberg
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-12-01
Subjects:	DNA methylation major histocompatibility complex multiple sclerosis differentially methylated regions DNA methylation quantitative trait loci
Online Access:	https://www.frontiersin.org/articles/10.3389/fneur.2023.1326738/full

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