Comparative analysis activation of post-receptor signal ways by dimeric dipeptide mimetiks of different loops of NGF

On culture of hippocampal HT-22 cells line it is shown that dimeric dipeptide mimetiks of different Loops of NGF realize their action via specific neurotrophic TrkA-receptor and selective activate post-receptor intracellular signal ways. Mimetiks of 1th (GK-6 (10-6M)) and the 3rd Loops (GTS-115 ((10...

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发表在:	Фармакокинетика и Фармакодинамика
Main Authors:	T. A. Antipova, I. O. Logvinov, S. V. Nikolaev, S. V. Kruglov, A. V. Tarasiuk, P. I. Antipov, T. A. Gudasheva, S. B. Seredenin
格式:	文件
语言:	俄语
出版:	LLC “Publisher OKI” 2016-03-01
主题:	ngf trk-a внутриклеточный сигналинг димерные дипептидные миметики intracellular signaling dimeric dipeptide mimetiks
在线阅读:	https://www.pharmacokinetica.ru/jour/article/view/168