Wound-healing and benzodiazepines: does sleep play a role in this relationship?

Patients who have suffered burns frequently experience psychological consequences, among which anxiety disorders are prominent. Benzodiazepines are commonly administered to treat these symptoms. The effects of benzodiazepines on healing may not be direct but rather are modulated by alterations of th...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Clinics
المؤلفون الرئيسيون: Flavia Egydio, Gabriel Natan Pires, Sergio Tufik, Monica Levy Andersen
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Elsevier España
الموضوعات:
benzodiazepines
sleep deprivation
wound healing
burns
immune system
الوصول للمادة أونلاين:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322012000700020&lng=en&tlng=en
الوصف
الملخص:Patients who have suffered burns frequently experience psychological consequences, among which anxiety disorders are prominent. Benzodiazepines are commonly administered to treat these symptoms. The effects of benzodiazepines on healing may not be direct but rather are modulated by alterations of the sleep architecture. This hypothesis is supported by studies that demonstrate the effects of benzodiazepines on the immune system and the inflammatory profile under both normal sleep conditions and during sleep deprivation, particularly rapid eye movement sleep deprivation.
تدمد:1807-5932
1980-5322

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