Deconstructing Pancreatic Cancer Using Next Generation-Omic Technologies–From Discovery to Knowledge-Guided Platforms for Better Patient Management

Comprehensive molecular landscaping studies reveal a potentially brighter future for pancreatic ductal adenocarcinoma (PDAC) patients. Blood-borne biomarkers obtained from minimally invasive “liquid biopsies” are now being trialled for early disease detection and to track responses to therapy. Integ...

Full description

Bibliographic Details
Published in:	Frontiers in Cell and Developmental Biology
Main Authors:	Daniel Schreyer, John P. Neoptolemos, Simon T. Barry, Peter Bailey
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-01-01
Subjects:	precision medicine omic pancreatic cancer molecular profiling and subtyping next-generation sequencing single-cell ‘omics
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2021.795735/full

Similar Items

Comprehensive multi-omics profiling identifies novel molecular subtypes of pancreatic ductal adenocarcinoma
by: Xing Wang, et al.
Published: (2024-11-01)

Clinical Impact of Molecular Subtyping of Pancreatic Cancer
by: Xu Zhou, et al.
Published: (2021-11-01)

Corrigendum: Clinical impact of molecular subtyping of pancreatic cancer
by: Xu Zhou, et al.
Published: (2023-03-01)

Visual analysis of multi-omics data
by: Austin Swart, et al.
Published: (2024-09-01)

Improving molecular subtypes and prognosis of pancreatic cancer through multi group analysis and machine learning
by: Xue-Jian Zhang, et al.
Published: (2025-01-01)

Multi-omics analyses inform mechanisms of immunotherapy response in pancreatic cancer
by: Mengyao Wu, et al.
Published: (2025-10-01)

Multi-omic biomarker panel in pancreatic cyst fluid and serum predicts patients at a high risk of pancreatic cancer development
by: Laura E. Kane, et al.
Published: (2025-01-01)

New discoveries in the field of metabolism by applying single-cell and spatial omics
by: Baocai Xie, et al.
Published: (2023-07-01)

Multi‐omic approaches for biomarker discovery in Moyamoya disease
by: Laura Gatti, et al.
Published: (2024-04-01)

Trans‐omic profiling between clinical phenoms and lipidomes among patients with different subtypes of lung cancer
by: Zhenhua Zhu, et al.
Published: (2020-08-01)

Nano‐omics: Frontier fields of fusion of nanotechnology
by: Xuan Wang, et al.
Published: (2023-11-01)

Recent advances in omics and the integration of multi-omics in osteoarthritis research
by: Ye Liu, et al.
Published: (2025-05-01)

Personalized analysis of human cancer multi-omics for precision oncology
by: Jiaao Li, et al.
Published: (2024-12-01)

Hypoxia within tumor microenvironment characterizes distinct genomic patterns and aids molecular subtyping for guiding individualized immunotherapy
by: Run Shi, et al.
Published: (2024-06-01)

Clustering analysis revealed the autophagy classification and potential autophagy regulators' sensitivity of pancreatic cancer based on multi‐omics data
by: Yonghao Chen, et al.
Published: (2023-01-01)

Enhancing precision medicine through clinical mass spectrometry platform
by: Julieta Hristova, et al.
Published: (2022-12-01)

Enhanced Cancer Subclassification Using Multi-Omics Clustering and Quantum Cat Swarm Optimization
by: Mazin Mohammed
Published: (2024-08-01)

HiOmics: A cloud-based one-stop platform for the comprehensive analysis of large-scale omics data
by: Wen Li, et al.
Published: (2024-12-01)

Application of single-cell and spatial omics in deciphering cellular hallmarks of cancer drug response and resistance
by: Xiaoxia Cheng, et al.
Published: (2025-07-01)

The role of multi-omics in biomarker discovery, diagnosis, prognosis, and therapeutic monitoring of tissue repair and regeneration processes
by: Jiamei Liu, et al.
Published: (2025-09-01)

Advanced Omics Techniques for Understanding Cochlear Genome, Epigenome, and Transcriptome in Health and Disease
by: Annamaria Tisi, et al.
Published: (2023-10-01)

Unveiling migraine subtype heterogeneity and risk loci: integrated genome-wide association study and single-cell transcriptomics discovery
by: Shuxu Wei, et al.
Published: (2025-08-01)

Cuproptosis-related gene CEP55 as a biomarker of pancreatic adenocarcinoma via multi-omics techniques and experimental validation
by: Zhang Riyuan, et al.
Published: (2025-07-01)

Editorial: Perspectives in omics 2022
by: Sophie Ayciriex, et al.
Published: (2023-10-01)

Precision nutrition management in hyperlipidemia-associated acute pancreatitis: mechanistic insights and personalized therapeutic approaches
by: Jingyuan Ma, et al.
Published: (2025-06-01)

Next-Generation Approaches in Sports Medicine: The Role of Genetics, Omics, and Digital Health in Optimizing Athlete Performance and Longevity—A Narrative Review
by: Alen Juginović, et al.
Published: (2025-06-01)

Machine learning and multi-omics data in chronic lymphocytic leukemia: the future of precision medicine?
by: Maria Tsagiopoulou, et al.
Published: (2024-01-01)

A multi-omics technology to the study of lactic acid bacteria responses to environmental stress: the past, current and future trends
by: Yaqi Liu, et al.
Published: (2025-07-01)

Cancer Subtype Identification Through Integrating Inter and Intra Dataset Relationships in Multi-Omics Data
by: Mark Peelen, et al.
Published: (2024-01-01)

Multi-omics analysis of an immune-based prognostic predictor in non-small cell lung cancer
by: Yang Zheng, et al.
Published: (2021-12-01)

Parallel Multi-Omics in High-Risk Subjects for the Identification of Integrated Biomarker Signatures of Type 1 Diabetes
by: Oscar Alcazar, et al.
Published: (2021-03-01)

OmicNavigator: open-source software for the exploration, visualization, and archival of omic studies
by: Terrence R. Ernst, et al.
Published: (2024-04-01)

Deep Learning Methods for Omics Data Imputation
by: Lei Huang, et al.
Published: (2023-10-01)

Editorial: Omics biomarkers in inflammatory ocular diseases
by: Masaru Ttakeuchi, et al.
Published: (2022-08-01)

Editorial: Multimodal and Integrative Analysis of Single-Cell or Bulk Sequencing Data
by: Geng Chen, et al.
Published: (2021-02-01)

Integrating Molecular Perspectives: Strategies for Comprehensive Multi-Omics Integrative Data Analysis and Machine Learning Applications in Transcriptomics, Proteomics, and Metabolomics
by: Pedro H. Godoy Sanches, et al.
Published: (2024-10-01)

Unsupervised subtyping and methylation landscape of pancreatic ductal adenocarcinoma
by: Shikha Roy, et al.
Published: (2021-01-01)

Multi-omics pan-cancer study of SPTBN2 and its value as a potential therapeutic target in pancreatic cancer
by: Hongliang Chang, et al.
Published: (2024-04-01)

Emerging pathological diagnostic strategies for solid pseudopapillary neoplasm of the pancreas: insights from omics and innovative techniques
by: Yuanhao Liu, et al.
Published: (2025-05-01)

Multi-omics: a bridge connecting genotype and phenotype for epilepsy?
by: Nan-Nan Wang, et al.
Published: (2025-06-01)