Broadening horizons: molecular mechanisms and disease implications of endothelial-to-mesenchymal transition

Abstract Endothelial-mesenchymal transition (EndMT) is defined as an important process of cellular differentiation by which endothelial cells (ECs) are prone to lose their characteristics and transform into mesenchymal cells. During EndMT, reduced expression of endothelial adhesion molecules disrupt...

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Bibliographic Details

Published in:	Cell Communication and Signaling
Main Authors:	Cheng Qian, Guanglu Dong, Chunmei Yang, Weiwei Zheng, Chongjin Zhong, Qiuhong Shen, Yin Lu, Yang Zhao
Format:	Article
Language:	English
Published:	BMC 2025-01-01
Subjects:	Endothelial-mesenchymal transition Endothelial cells Mesenchymal phenotype Non-coding RNA TGF-β signaling pathway
Online Access:	https://doi.org/10.1186/s12964-025-02028-y