Editorial Comments to the Special Issue: “<em>Aggregatibacter actinomycetemcomitans</em>—Gram-Negative Bacterial Pathogen”
<i>Aggregatibacter actinomycetemcomitans</i> is a periodontal pathogen colonizing the oral cavity in many individuals of the human population. It is equipped with several potent virulence factors that can cause cell death and induce or evade the host inflammatory response. Both harmless...
| Published in: | Pathogens |
|---|---|
| Main Authors: | , , |
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-06-01
|
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-0817/9/6/441 |
| _version_ | 1849891818688217088 |
|---|---|
| author | Jan Oscarsson Joseph DiRienzo Anders Johansson |
| author_facet | Jan Oscarsson Joseph DiRienzo Anders Johansson |
| author_sort | Jan Oscarsson |
| collection | DOAJ |
| container_title | Pathogens |
| description | <i>Aggregatibacter actinomycetemcomitans</i> is a periodontal pathogen colonizing the oral cavity in many individuals of the human population. It is equipped with several potent virulence factors that can cause cell death and induce or evade the host inflammatory response. Both harmless and highly virulent genotypes of the bacterium have emerged because of the large genetic diversity within the species. The oral condition and age, as well as the geographic origin of the individual, influence the risk to be colonized by a virulent genotype of the bacterium. In the present editorial, the different genetic and virulence properties of <i>A. actinomycetemcomitans</i> will be addressed in relation to the publications in this Special Issue. |
| format | Article |
| id | doaj-art-e2044502811a44b4b0d006403b8e4806 |
| institution | Directory of Open Access Journals |
| issn | 2076-0817 |
| language | English |
| publishDate | 2020-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| spelling | doaj-art-e2044502811a44b4b0d006403b8e48062025-08-20T01:03:27ZengMDPI AGPathogens2076-08172020-06-019644110.3390/pathogens9060441Editorial Comments to the Special Issue: “<em>Aggregatibacter actinomycetemcomitans</em>—Gram-Negative Bacterial Pathogen”Jan Oscarsson0Joseph DiRienzo1Anders Johansson2Department of Odontology, Umeå University, S-901 87 Umeå, SwedenDepartment of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104-6030, USADepartment of Odontology, Umeå University, S-901 87 Umeå, Sweden<i>Aggregatibacter actinomycetemcomitans</i> is a periodontal pathogen colonizing the oral cavity in many individuals of the human population. It is equipped with several potent virulence factors that can cause cell death and induce or evade the host inflammatory response. Both harmless and highly virulent genotypes of the bacterium have emerged because of the large genetic diversity within the species. The oral condition and age, as well as the geographic origin of the individual, influence the risk to be colonized by a virulent genotype of the bacterium. In the present editorial, the different genetic and virulence properties of <i>A. actinomycetemcomitans</i> will be addressed in relation to the publications in this Special Issue.https://www.mdpi.com/2076-0817/9/6/441<i>Aggregatibacter actinomycetemcomitans</i>leukotoxincytolethal distending toxinlipopolysaccharidescytokine binding factorshorizontal gene transfer |
| spellingShingle | Jan Oscarsson Joseph DiRienzo Anders Johansson Editorial Comments to the Special Issue: “<em>Aggregatibacter actinomycetemcomitans</em>—Gram-Negative Bacterial Pathogen” <i>Aggregatibacter actinomycetemcomitans</i> leukotoxin cytolethal distending toxin lipopolysaccharides cytokine binding factors horizontal gene transfer |
| title | Editorial Comments to the Special Issue: “<em>Aggregatibacter actinomycetemcomitans</em>—Gram-Negative Bacterial Pathogen” |
| title_full | Editorial Comments to the Special Issue: “<em>Aggregatibacter actinomycetemcomitans</em>—Gram-Negative Bacterial Pathogen” |
| title_fullStr | Editorial Comments to the Special Issue: “<em>Aggregatibacter actinomycetemcomitans</em>—Gram-Negative Bacterial Pathogen” |
| title_full_unstemmed | Editorial Comments to the Special Issue: “<em>Aggregatibacter actinomycetemcomitans</em>—Gram-Negative Bacterial Pathogen” |
| title_short | Editorial Comments to the Special Issue: “<em>Aggregatibacter actinomycetemcomitans</em>—Gram-Negative Bacterial Pathogen” |
| title_sort | editorial comments to the special issue em aggregatibacter actinomycetemcomitans em gram negative bacterial pathogen |
| topic | <i>Aggregatibacter actinomycetemcomitans</i> leukotoxin cytolethal distending toxin lipopolysaccharides cytokine binding factors horizontal gene transfer |
| url | https://www.mdpi.com/2076-0817/9/6/441 |
| work_keys_str_mv | AT janoscarsson editorialcommentstothespecialissueemaggregatibacteractinomycetemcomitansemgramnegativebacterialpathogen AT josephdirienzo editorialcommentstothespecialissueemaggregatibacteractinomycetemcomitansemgramnegativebacterialpathogen AT andersjohansson editorialcommentstothespecialissueemaggregatibacteractinomycetemcomitansemgramnegativebacterialpathogen |