Diagnosis and management of radiation cholecystitis as a complication of Y90 radioembolization for hepatocellular carcinoma

• Published in: Radiology Case Reports
• Main Authors: Joe Khoury, DO, MBA, Brenden Li, BS, Joyce Zhu, BS, Trevor Lin, BS, Eusha Hasan, BA, Ashley Lamba, BS, Vaiva Gustainyte, DO, Hakob Kocharyan, MD, Christopher Yeisley, MD, Elias Salloum, MD, Altan Ahmed, MD, Craig Greben, MD, Mustafa Al-Roubaie, MD
• Format: Article
• Language: English
• Published: Elsevier 2024-08-01
• Subjects: Radioembolization; Y90; Radiation cholecystitis; Hepatocellular carcinoma; Interventional oncology
• Online Access: http://www.sciencedirect.com/science/article/pii/S1930043324003972
• ISSN: 1930-0433

Radiation induced cholecystitis is a known but rare complication of Yttrium90 (Y90) radioembolization of hepatic tumors due to nontarget embolization. Many documented cases of radiation induced cholecystitis have been treated with cholecystectomy, which is significant given the typical patient population undergoing radioembolization tends to be of higher surgical risk. Here, we present a case of a 68 year old male who developed radiation induced cholecystitis status post hepatic radioembolization that resolved with conservative management alone. This case highlights that radiation induced cholecystitis may be successfully and safely treated conservatively.