Mycobacterial Hsp65 antigen upregulates the cellular immune response of healthy individuals compared with tuberculosis patients

Previously we showed that 65-kDa Mycobacterium leprae heat shock protein (Hsp65) is a target for the development of a tuberculosis vaccine. Here we evaluated peripheral blood mononuclear cells (PBMC) from healthy individuals or tuberculosis patients stimulated with two forms of Hsp65 antigen, recomb...

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Bibliographic Details

Published in:	Human Vaccines & Immunotherapeutics
Main Authors:	Pryscilla Fanini Wowk, Luís Henrique Franco, Denise Morais da Fonseca, Marina Oliveira Paula, Élcio dos Santos Oliveira Vianna, Ana Paula Wendling, Valéria Maria Augusto, Silvana Maria Elói-Santos, Andréa Teixeira-Carvalho, Flávia Dias Coelho Silva, Solange Alves Vinhas, Olindo Assis Martins-Filho, Moisés Palaci, Célio Lopes Silva, Vânia Luiza Deperon Bonato
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2017-05-01
Subjects:	ifn-γ il-10 tuberculosis vaccine
Online Access:	http://dx.doi.org/10.1080/21645515.2016.1264547