Losartan Alleviates the Side Effects and Maintains the Anticancer Activity of Axitinib

Axitinib is one of the most potent inhibitors of the vascular endothelial growth factor (VEGF) receptor and shows strong antitumor activity toward various malignant tumors. However, its severe side effects affect the quality of life and prognosis of patients. Losartan, which functions as a typical a...

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Bibliographic Details

Published in:	Molecules
Main Authors:	Ying Fu, Rengui Saxu, Kadir Ahmad Ridwan, Jiaping Yao, Xiaoxuan Chen, Xueping Xu, Weida Zheng, Peng Yu, Yuou Teng
Format:	Article
Language:	English
Published:	MDPI AG 2022-04-01
Subjects:	axitinib VEGF receptor inhibitor losartan angiotensin receptor blockers side effect antitumor
Online Access:	https://www.mdpi.com/1420-3049/27/9/2764