Nocturnal dipping of heart rate and blood pressure in people with HIV in Tanzania

Abstract People with HIV (PWH) have a >2‐fold greater risk for development of cardiovascular disease (CVD), which may be associated with abnormalities in 24‐h ambulatory blood pressure measurement (ABPM) profile. We conducted a nested case‐control study of ABPM in 137 PWH and HIV‐uninfected contr...

Full description

Bibliographic Details
Published in:The Journal of Clinical Hypertension
Main Authors: Cody Nolan, Karl Reis, Salama Fadhil, Anthony Etyang, Chiomah Ezeomah, Justin R. Kingery, Bernard Desderius, Myung‐Hee Lee, Saidi Kapiga, Robert N. Peck
Format: Article
Language:English
Published: Wiley 2021-07-01
Subjects:
ambulatory blood pressure monitoring
HIV
nocturnal blood pressure
nocturnal heart rate
sub‐Saharan Africa
Online Access:https://doi.org/10.1111/jch.14300
Description
Summary:Abstract People with HIV (PWH) have a >2‐fold greater risk for development of cardiovascular disease (CVD), which may be associated with abnormalities in 24‐h ambulatory blood pressure measurement (ABPM) profile. We conducted a nested case‐control study of ABPM in 137 PWH and HIV‐uninfected controls with normal and high clinic blood pressure (BP) in Tanzania. Nocturnal non‐dipping of heart rate (HR) was significantly more common among PWH than HIV‐uninfected controls (p = .01). Nocturnal non‐dipping of BP was significantly more common in PWH with normal clinic BP (p = .048). Clinical correlates of nocturnal non‐dipping were similar in PWH and HIV‐uninfected adults and included higher BMI, higher CD4+ cell count, and high C‐reactive protein for HR and markers of renal disease for BP. In conclusion, nocturnal non‐dipping of both BP and HR was more common in PWH but further research is needed to determine causes and consequences of this difference.
ISSN:1524-6175
1751-7176

Similar Items