POSSIBILITIES OF USING THE GENOTYPING OF CYTOKINES WITH INFLAMMATION-REGULATORY ACTIVITY AS BIOLOGICAL MARKERS FOR PREDICTION OF THE EFFICIENCY OF THERAPY FOR RHEUMATOID ARTHRITIS

Objective. To reveal the genetic markers that may predict the efficiency of therapy for rheumatoid arthritis (RA). Subjects and methods. The study enrolled 104 patients (93 women and 11 men) (mean age 53.38+13.55 years). The duration of RA averaged 9.18+8.97 years. The patients were treated with bas...

Full description

Bibliographic Details
Published in:	Научно-практическая ревматология
Main Authors:	Vladimir Iosifovich Konenkov, E V Zonova, Yu B Leonova, M A Korolev, V F Prokof'ev, O V Golovanova, A V Shevchenko, V F Prokofyev
Format:	Article
Language:	Russian
Published:	IMA PRESS LLC 2010-10-01
Subjects:	rheumatoid arthritis basic anti-inflammatory drugs genetic markers proinflammatory and anti-inflammatory cytokines polymorphism
Online Access:	https://rsp.mediar-press.net/rsp/article/view/863

Similar Items

COMBINATION ANALYSIS OF CYTOKINE GENE PROMOTER POLYMORPHISMS OF IL1B T-31C, IL-6 G-174C, TNFA G-238A, TNFA G-308A, TNFA C-863A, IL4 C-590T, IL-10 C-592A FOR PREDICTION OF TREATMENT EFFICIENCY IN RHEUMATOID ARTHRITIS
by: V. I. Konenkov, et al.
Published: (2014-07-01)

INFLAMMATION AS A THERAPEUTIC TARGET IN THE COMPLEX TREATMENT OF MALIGNANT TUMORS
by: O. E. Savelieva, et al.
Published: (2017-07-01)

KOMPLEKSNYY ANALIZ KLINIChESKOY ZNAChIMOSTI VYYaVLENIYaALLEL'NYKh VARIANTOV GENOV TsITOKINOV IL1B, IL6, IL10, TNFA IFAKTORA ROSTA VEGF V KAChESTVE GENETIChESKIKh FAKTOROV RISKARAZVITIYa OSTEOPOROZA PRI SAKhARNOM DIABETE 2 TIPA
by: V I Konenkov, et al.
Published: (2010-12-01)

Pro-inflammatory and anti-inflammatory cytokines in neonates during the acute period of novel coronavirus infection
by: E. V. Moskaleva, et al.
Published: (2024-12-01)

CYTOKINE PROFILE IN PATIENTS WITH CHRONIC VIRUS HEPATITIS COMPLICATED WITH FIBROSIS AND CIRRHOSIS
by: E. R. Chernykh, et al.
Published: (2014-07-01)

A sound approach to choosing nonsteroidal anti-inflammatory drugs for osteoarthritis
by: E. V. Zonova, et al.
Published: (2018-12-01)

Exosomes secreted by Blastocystis subtypes affect the expression of proinflammatory and anti-inflammatory cytokines (TNFα, IL-6, IL-10, IL-4)
by: Mojtaba Norouzi, et al.
Published: (2022-08-01)

Interleukins in lacrimal fluid and diabetic retinopathy
by: I. V. Lev, et al.
Published: (2022-07-01)

DIAGNOSTIC VALUE OF STUDYING THE LEVELS OF PRO- AND ANTI-INFLAMMATORY CYTOKINES OF THE IMMUNE SYSTEM IN PATIENTS WITH BREAST CANCER
by: L. T. Alimkhodjaeva
Published: (2014-09-01)

COMBINATIONS OF CYTOKINE AND MATRIX METALLOPROTEINASE GENES ASSOCIATED WITH RETINOPATHY IN TYPE 2 DIABETIC WOMEN
by: V. I. Konenkov, et al.
Published: (2015-12-01)

Combinations of cytokine and matrix metalloproteinase genes associated with retinopathy in type 2 diabetic women
by: V.I. Konenkov,, et al.
Published: (2013-04-01)

GENETIC FACTORS INDUCING DISTURBED REGULATION OF ANGIOGENESIS IN DIABETES MELLITUS TYPE 2
by: V. I. Konenkov, et al.
Published: (2014-07-01)

CYTOKINE REGULATION IN THE COURSE OF MULTIPLE MYELOMA PROGRESSION
by: O. V. Smirnova, et al.
Published: (2015-06-01)

The analysis of MMP2, MMP3 and MMP9 matrix metalloproteinases genes polymorphism among Russian Caucasian patients with primary open-angle glaucoma
by: A.V. Shevchenko, et al.
Published: (2023-03-01)

GENE POLYMORPHISMS OF ENDOTHELIAL DYSFUNCTION, COACTIVATORS OF MITOCHONDRIAL BIOGENESIS AND PLASMINOGEN/PLASMIN SYSTEM IN THE DEVELOPMENT OF CARDIOVASCULAR EVENTS IN RHEUMATOID ARTHRITIS
by: A. V. Shevchenko, et al.
Published: (2018-03-01)

Vascular endothelial growth factor (VEGF-2578А/С) gene polymorphism in combination with cytokine gene polymorphisms among patients with rheumatoid arthritis
by: V I Konenkov, et al.
Published: (2013-06-01)

Antibacterial and anti-inflammatory activities of an extract, fractions, and compounds isolated from Gochnatia pulchra aerial parts
by: R. Lucarini, et al.
Published: (2015-01-01)

Associations of vascular endothelial growth factor (VEGF) gene and cytokine (IL-1B, IL-4, IL-6, IL-10, TNFA) genes combinations with type 2 diabetes mellitus in women
by: Vladimir Iosifovich Konenkov, et al.
Published: (2012-09-01)

In vitro activity of anti-rheumatic drugs on release of pro-inflammatory cytokines from oral cells in interaction with microorganisms
by: Alexandra Stähli, et al.
Published: (2022-09-01)

Erratum: In vitro activity of anti-rheumatic drugs on release of pro-inflammatory cytokines from oral cells in interaction with microorganisms
by: Frontiers Production Office
Published: (2023-03-01)

ASSOCIATION OF LETHAL OUTCOMES IN SURGICAL SEPSIS WITH ALLELIC VARIANTS OF TNF Α AND HEAT SHOCK PROTEIN (HSP70-2) GENES
by: A. V. Shevchenko, et al.
Published: (2014-07-01)

LONG-TERM OUTCOMES IN RHEUMATOID ARTHRITIS IN RELATION TO THE TIME AFTER THE INITIATIONOF BASIC ANTI-INFLAMMATORY DRUG THERAPY
by: Natalya Vladimirovna Chichasova, et al.
Published: (2010-06-01)

Prostacyclin Regulation of Allergic Inflammation
by: Kunj Patel, et al.
Published: (2022-11-01)

Polymorphism in the regulatory regions –С2578A and +C936T of the vascular endothelial growth factor (VEGF-A) gene in Russian women with rheumatoid arthritis
by: A V Shevchenko, et al.
Published: (2017-05-01)

Some features of osteogenesis in ankylosing spondylitis and the possibilities of treatment with bisphosphonates
by: A. V. Datsina, et al.
Published: (2024-06-01)

Pro- and anti-inflammatory cytokines and growth factors in patients undergoing in vitro fertilization procedure treated with prednisone
by: Karolina Piekarska, et al.
Published: (2023-09-01)

<i>In vitro</i> effects of intestinal microsymbionts on the cytokine production
by: O. V. Bukharin, et al.
Published: (2023-11-01)

The use of methotrexate in rheumatoid arthritis. Recommendations of the All-Russian public organization “Association of Rheumatologists of Russia”
by: E. L. Nasonov, et al.
Published: (2023-08-01)

Early hyperlipidemia triggers metabolomic reprogramming with increased SAH, increased acetyl-CoA-cholesterol synthesis, and decreased glycolysis
by: Keman Xu, et al.
Published: (2023-08-01)

Association of TNF-α gene promoter polymorphism with primary open-angle glaucoma
by: A.V. Shevchenko, et al.
Published: (2022-02-01)

Chemical Diversity of Soft Coral Steroids and Their Pharmacological Activities
by: Ekaterina V. Ermolenko, et al.
Published: (2020-12-01)

EFFECT OF CRYOPRESERVED PLACENTA EXTRACT ON SOME BIOCHEMICAL INDICES OF THERAPEUTIC EFFICIENCY AND TOXICITY OF DICLOFENAC SODIUM IN ADJUVANT-INDUCED EXPERIMENTAL ARTHRITIS
by: F. V. Hladkykh, et al.
Published: (2021-09-01)

Genetic and cellular techniques emerge as promising modalities for the treatment of diabetic foot syndrome
by: Vladimir Iosifovich Konenkov, et al.
Published: (2014-03-01)

Evaluation of the efficacy of standard basic anti-inflammatory drugs and the time to start basictherapy for rheumatoid arthritis
by: Irina Mikhailovna Marusenko
Published: (2010-12-01)

Janus kinase inhibitors in the treatment of psoriatic arthritis
by: E. Yu. Loginova, et al.
Published: (2022-02-01)

Clinical importance of cytokine (IL-6, IL-8, and IL-10) and vitamin D levels among patients with Type-1 diabetes
by: Azharuddin Sajid Syed Khaja, et al.
Published: (2024-10-01)

Atherosclerosis and inflammation: Current therapeutic strategies. A review
by: Marina Yu. Zubareva, et al.
Published: (2024-05-01)

Nonsteroidal anti-inflammatory drugs: What is new in international publications in 2015?
by: A. E. Karateev, et al.
Published: (2016-03-01)

Synthesis and Anti-Inflammatory Activity of (<i>Z</i>)-4-(2-(3-Oxopiperazin-2-ylidene)acetyl)benzoic Acid
by: Maksim V. Dmitriev, et al.
Published: (2024-02-01)

Predominant pro-inflammatory environment in mid-gestation pregnant women with history of recurrent pregnancy loss: a South Indian study
by: Rashmi Bhuwalka, et al.
Published: (2025-04-01)