The role of hexokinases in epigenetic regulation: altered hexokinase expression and chromatin stability in yeast

Abstract Background Human hexokinase 2 (HK2) plays an important role in regulating Warburg effect, which metabolizes glucose to lactate acid even in the presence of ample oxygen and provides intermediate metabolites to support cancer cell proliferation and tumor growth. HK2 overexpression has been o...

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Bibliographic Details

Published in:	Epigenetics & Chromatin
Main Authors:	Srinivasu Karri, Quinn Dickinson, Jing Jia, Yi Yang, Haiyun Gan, Zhiquan Wang, Yibin Deng, Chuanhe Yu
Format:	Article
Language:	English
Published:	BMC 2024-08-01
Subjects:	Hexokinase 2-deoxy-D-glucose Histone chaperones eSPAN Chromatin replication Yeast
Online Access:	https://doi.org/10.1186/s13072-024-00551-9