Frequent use of IGHV3-30-3 in SARS-CoV-2 neutralizing antibody responses

The antibody response to SARS-CoV-2 shows biased immunoglobulin heavy chain variable (IGHV) gene usage, allowing definition of genetic signatures for some classes of neutralizing antibodies. We investigated IGHV gene usage frequencies by sorting spike-specific single memory B cells from individuals...

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Bibliographic Details
Published in:	Frontiers in Virology
Main Authors:	Pradeepa Pushparaj, Andrea Nicoletto, Xaquin Castro Dopico, Daniel J. Sheward, Sungyong Kim, Simon Ekström, Ben Murrell, Martin Corcoran, Gunilla B. Karlsson Hedestam
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-03-01
Subjects:	SARS-CoV-2 immunoglobulin germline genes allelic diversity copy number variation antibodies
Online Access:	https://www.frontiersin.org/articles/10.3389/fviro.2023.1128253/full

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