Virus adaptation to heparan sulfate comes with capsid stability tradeoff

Because of high mutation rates, viruses constantly adapt to new environments. When propagated in cell lines, certain viruses acquire positively charged amino acids on their surface proteins, enabling them to utilize negatively charged heparan sulfate (HS) as an attachment receptor. In this study, we...

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التفاصيل البيبلوغرافية
الحاوية / القاعدة:eLife
المؤلفون الرئيسيون: Han Kang Tee, Simon Crouzet, Arunima Muliyil, Gregory Mathez, Valeria Cagno, Matteo Dal Peraro, Aleksandar Antanasijevic, Sophie Clément, Caroline Tapparel
التنسيق: مقال
اللغة:الإنجليزية
منشور في: eLife Sciences Publications Ltd 2024-12-01
الموضوعات:
الوصول للمادة أونلاين:https://elifesciences.org/articles/98441

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