Adenovirus-mediated delivery of bFGF small interfering RNA reduces STAT3 phosphorylation and induces the depolarization of mitochondria and apoptosis in glioma cells U251
<p>Abstract</p> <p>Glioblastoma multiforme (GBM) carries a dismal prognosis primarily due to its aggressive proliferation in the brain regulated by complex molecular mechanisms. One promising molecular target in GBM is over-expressed basic fibroblast growth factor (bFGF), which has...
| الحاوية / القاعدة: | Journal of Experimental & Clinical Cancer Research |
|---|---|
| المؤلفون الرئيسيون: | , , , , |
| التنسيق: | مقال |
| اللغة: | الإنجليزية |
| منشور في: |
BMC
2011-09-01
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| الموضوعات: | |
| الوصول للمادة أونلاين: | http://www.jeccr.com/content/30/1/80 |