Shikonin Inhibits APC-mutant Colon Cancer via Wnt/β-catenin Signaling

Objective To identify small molecule inhibitors of APC-mutant colon cancer and provide lead compounds for targeted therapy of colon cancer. MethodsAPC-mutant colon cancer cell lines that stably express 7*Tcf-GFP/SV40-Cherry (7TGC) dual fluorescence reporter system was constructed for small-molecule...

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Bibliographic Details
Published in:	Zhongliu Fangzhi Yanjiu
Main Authors:	Lizhe CHEN, Bojun WANG, Qing GONG, Xue ZHANG, Xisong KE
Format:	Article
Language:	Chinese
Published:	Magazine House of Cancer Research on Prevention and Treatment 2024-06-01
Subjects:	apc mutation colon cancer wnt/β-catenin signaling shikonin
Online Access:	http://www.zlfzyj.com/cn/article/doi/10.3971/j.issn.1000-8578.2024.24.0121

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