Developments for collagen hydrolysates as a multifunctional antioxidant in biomedical domains
Abstract Antioxidant collagen hydrolysates refers to the peptides mixture with antioxidant properties identified from hydrolyzed collagen. Due to its specific structural, biological and physicochemical properties, collagen hydrolysates have been explored as a multifunctional antioxidant in the biome...
| Published in: | Collagen and Leather |
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| Main Authors: | , , , , , , , , , |
| Format: | Article |
| Language: | English |
| Published: |
SpringerOpen
2023-09-01
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| Subjects: | |
| Online Access: | https://doi.org/10.1186/s42825-023-00131-9 |
| _version_ | 1851833223134314496 |
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| author | Guiya Deng Ke Huang Xianchao Jiang Kun Wang Zihao Song Yuchen Su Chengming Li Shuai Zhang Shiqi Wang Yaqin Huang |
| author_facet | Guiya Deng Ke Huang Xianchao Jiang Kun Wang Zihao Song Yuchen Su Chengming Li Shuai Zhang Shiqi Wang Yaqin Huang |
| author_sort | Guiya Deng |
| collection | DOAJ |
| container_title | Collagen and Leather |
| description | Abstract Antioxidant collagen hydrolysates refers to the peptides mixture with antioxidant properties identified from hydrolyzed collagen. Due to its specific structural, biological and physicochemical properties, collagen hydrolysates have been explored as a multifunctional antioxidant in the biomedical field. In this review, we summarize recent advances in antioxidant collagen hydrolysates development. Initially, the preparation process of antioxidant collagen hydrolysates is introduced, including the production and separation methods. Then the effects and the mechanisms of amino acid composition and collagen peptide structure on the antioxidant activity of collagen hydrolysates are reviewed. Finally, the applications of antioxidant collagen hydrolysates in biomedical domains are summarized, with critical discussions about the advantages, current limitations and challenges to be resolved in the future. Graphical abstract |
| format | Article |
| id | doaj-art-e2ef1d9aca74404a8d4df9ca939e7e4e |
| institution | Directory of Open Access Journals |
| issn | 2097-1419 2731-6998 |
| language | English |
| publishDate | 2023-09-01 |
| publisher | SpringerOpen |
| record_format | Article |
| spelling | doaj-art-e2ef1d9aca74404a8d4df9ca939e7e4e2025-08-19T22:31:20ZengSpringerOpenCollagen and Leather2097-14192731-69982023-09-015112110.1186/s42825-023-00131-9Developments for collagen hydrolysates as a multifunctional antioxidant in biomedical domainsGuiya Deng0Ke Huang1Xianchao Jiang2Kun Wang3Zihao Song4Yuchen Su5Chengming Li6Shuai Zhang7Shiqi Wang8Yaqin Huang9Beijing Laboratory of Biomedical Materials, Key Laboratory of Biomedical Materials of Natural Macromolecules (Beijing University of Chemical Technology), Ministry of Education, Beijing University of Chemical TechnologyBeijing Laboratory of Biomedical Materials, Key Laboratory of Biomedical Materials of Natural Macromolecules (Beijing University of Chemical Technology), Ministry of Education, Beijing University of Chemical TechnologyBeijing Laboratory of Biomedical Materials, Key Laboratory of Biomedical Materials of Natural Macromolecules (Beijing University of Chemical Technology), Ministry of Education, Beijing University of Chemical TechnologyBeijing Laboratory of Biomedical Materials, Key Laboratory of Biomedical Materials of Natural Macromolecules (Beijing University of Chemical Technology), Ministry of Education, Beijing University of Chemical TechnologyBeijing Laboratory of Biomedical Materials, Key Laboratory of Biomedical Materials of Natural Macromolecules (Beijing University of Chemical Technology), Ministry of Education, Beijing University of Chemical TechnologyBeijing Laboratory of Biomedical Materials, Key Laboratory of Biomedical Materials of Natural Macromolecules (Beijing University of Chemical Technology), Ministry of Education, Beijing University of Chemical TechnologyBeijing Laboratory of Biomedical Materials, Key Laboratory of Biomedical Materials of Natural Macromolecules (Beijing University of Chemical Technology), Ministry of Education, Beijing University of Chemical TechnologySchool of Pharmacy, Queen’s University BelfastDrug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of HelsinkiBeijing Laboratory of Biomedical Materials, Key Laboratory of Biomedical Materials of Natural Macromolecules (Beijing University of Chemical Technology), Ministry of Education, Beijing University of Chemical TechnologyAbstract Antioxidant collagen hydrolysates refers to the peptides mixture with antioxidant properties identified from hydrolyzed collagen. Due to its specific structural, biological and physicochemical properties, collagen hydrolysates have been explored as a multifunctional antioxidant in the biomedical field. In this review, we summarize recent advances in antioxidant collagen hydrolysates development. Initially, the preparation process of antioxidant collagen hydrolysates is introduced, including the production and separation methods. Then the effects and the mechanisms of amino acid composition and collagen peptide structure on the antioxidant activity of collagen hydrolysates are reviewed. Finally, the applications of antioxidant collagen hydrolysates in biomedical domains are summarized, with critical discussions about the advantages, current limitations and challenges to be resolved in the future. Graphical abstracthttps://doi.org/10.1186/s42825-023-00131-9Collagen hydrolysatesAntioxidantPeptidesBiomedical applications |
| spellingShingle | Guiya Deng Ke Huang Xianchao Jiang Kun Wang Zihao Song Yuchen Su Chengming Li Shuai Zhang Shiqi Wang Yaqin Huang Developments for collagen hydrolysates as a multifunctional antioxidant in biomedical domains Collagen hydrolysates Antioxidant Peptides Biomedical applications |
| title | Developments for collagen hydrolysates as a multifunctional antioxidant in biomedical domains |
| title_full | Developments for collagen hydrolysates as a multifunctional antioxidant in biomedical domains |
| title_fullStr | Developments for collagen hydrolysates as a multifunctional antioxidant in biomedical domains |
| title_full_unstemmed | Developments for collagen hydrolysates as a multifunctional antioxidant in biomedical domains |
| title_short | Developments for collagen hydrolysates as a multifunctional antioxidant in biomedical domains |
| title_sort | developments for collagen hydrolysates as a multifunctional antioxidant in biomedical domains |
| topic | Collagen hydrolysates Antioxidant Peptides Biomedical applications |
| url | https://doi.org/10.1186/s42825-023-00131-9 |
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