Clinical, Neurophysiological, and Genetic Predictors of Recovery in Patients With Severe Acquired Brain Injuries (PRABI): A Study Protocol for a Longitudinal Observational Study

BackgroundDue to continuous advances in intensive care technology and neurosurgical procedures, the number of survivors from severe acquired brain injuries (sABIs) has increased considerably, raising several delicate ethical issues. The heterogeneity and complex nature of the neurological damage of...

Full description

Bibliographic Details
Published in:	Frontiers in Neurology
Main Authors:	Bahia Hakiki, Ida Donnini, Anna Maria Romoli, Francesca Draghi, Daniela Maccanti, Antonello Grippo, Maenia Scarpino, Antonio Maiorelli, Raisa Sterpu, Tiziana Atzori, Andrea Mannini, Silvia Campagnini, Silvia Bagnoli, Assunta Ingannato, Benedetta Nacmias, Francesco De Bellis, Anna Estraneo, Valentina Carli, Eugenia Pasqualone, Angela Comanducci, Jorghe Navarro, Maria Chiara Carrozza, Claudio Macchi, Francesca Cecchi
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-02-01
Subjects:	severe acquired brain injuries neurophysiology genetics disorders of consciousness rehabilitation
Online Access:	https://www.frontiersin.org/articles/10.3389/fneur.2022.711312/full

Similar Items

Merging Clinical and EEG Biomarkers in an Elastic-Net Regression for Disorder of Consciousness Prognosis Prediction
by: Piergiuseppe Liuzzi, et al.
Published: (2022-01-01)

Stroke-related epilepsy in the rehabilitation setting: Insights from the inpatient post-stroke rehabilitation study – RIPS
by: Maenia Scarpino, et al.
Published: (2024-01-01)

Cross-validation of predictive models for functional recovery after post-stroke rehabilitation
by: Silvia Campagnini, et al.
Published: (2022-09-01)

Critical Illness Polyneuropathy and Myopathy and Clinical Detection of the Recovery of Consciousness in Severe Acquired Brain Injury Patients with Disorders of Consciousness after Rehabilitation
by: Bahia Hakiki, et al.
Published: (2022-02-01)

Prediction of the functional outcome of intensive inpatient rehabilitation after stroke using machine learning methods
by: Silvia Campagnini, et al.
Published: (2025-05-01)

Correction: Prediction of the functional outcome of intensive inpatient rehabilitation after stroke using machine learning methods
by: Silvia Campagnini, et al.
Published: (2025-09-01)

Brain microstate spatio-temporal dynamics as a candidate endotype of consciousness
by: Piergiuseppe Liuzzi, et al.
Published: (2024-01-01)

The Impact of Cerebral Amyloid Angiopathy on Functional Outcome of Patients Affected by Spontaneous Intracerebral Hemorrhage Discharged from Intensive Inpatient Rehabilitation: A Cohort Study
by: Carmen Barbato, et al.
Published: (2022-10-01)

Cognitive reserve index and long-term disability in patients with severe traumatic brain injury discharged from the intensive rehabilitation unit
by: Bahia Hakiki, et al.
Published: (2023-05-01)

Can Respiration Complexity Help the Diagnosis of Disorders of Consciousness in Rehabilitation?
by: Piergiuseppe Liuzzi, et al.
Published: (2023-01-01)

Neural coding of autonomic functions in different states of consciousness
by: Piergiuseppe Liuzzi, et al.
Published: (2023-07-01)

Multiple imputation integrated to machine learning: predicting post-stroke recovery of ambulation after intensive inpatient rehabilitation
by: Alice Finocchi, et al.
Published: (2024-10-01)

MoCA Domain-Specific Pattern of Cognitive Impairment in Stroke Patients Attending Intensive Inpatient Rehabilitation: A Prospective Study
by: Benedetta Basagni, et al.
Published: (2024-01-01)

Design and implementation of a Stroke Rehabilitation Registry for the systematic assessment of processes and outcomes and the development of data-driven prediction models: The STRATEGY study protocol
by: Marco Chiavilli, et al.
Published: (2022-10-01)

Electrophysiological-based automatic subgroups diagnosis of patients with chronic dysimmune polyneuropathies
by: Sara Ballanti, et al.
Published: (2025-07-01)

Extra-Linguistic Cognitive Functions Involved in the Token Test: Results from a Cohort of Non-Aphasic Stroke Patients with Right Hemisphere Lesion
by: Benedetta Basagni, et al.
Published: (2022-12-01)

Cross-cultural adaptation and multicentric validation of the Italian version of the Simplified Evaluation of CONsciousness Disorders (SECONDs).
by: Bahia Hakiki, et al.
Published: (2025-01-01)

The epidemiology of malaria in Prábis, Guinea-Bissau
by: Aldina Gonçalves, et al.
Published: (1996-02-01)

Plasma GFAP, NfL and pTau 181 detect preclinical stages of dementia
by: Assunta Ingannato, et al.
Published: (2024-04-01)

Neurofilament Light Chain and Intermediate HTT Alleles as Combined Biomarkers in Italian ALS Patients
by: Assunta Ingannato, et al.
Published: (2021-09-01)

Comparing the effects of augmented virtual reality treadmill training versus conventional treadmill training in patients with stage II-III Parkinson’s disease: the VIRTREAD-PD randomized controlled trial protocol
by: Gemma Lombardi, et al.
Published: (2024-01-01)

Estimation of Spatiotemporal Gait Parameters in Walking on a Photoelectric System: Validation on Healthy Children by Standard Gait Analysis
by: Silvia Campagnini, et al.
Published: (2023-06-01)

Diagnostic yield of electroencephalographyin the emergency department: protocol for the EMINENCE-M multicentre retrospective observational study
by: Benedetta Piccardi, et al.
Published: (2026-06-01)

Putative novel CSF biomarkers of Alzheimer’s disease based on the novel concept of generic protein misfolding and proteotoxicity: the PRAMA cohort
by: Alessandra Bigi, et al.
Published: (2024-03-01)

Targeting Protein Aggregation in ALS
by: Michele Perni, et al.
Published: (2024-10-01)

The Effect of CAG Repeats within the Non-Pathological Range in the HTT Gene on Cognitive Functions in Patients with Subjective Cognitive Decline and Mild Cognitive Impairment
by: Valentina Bessi, et al.
Published: (2021-06-01)

Comparison between Ischemic and Hemorrhagic Strokes in Functional Outcome at Discharge from an Intensive Rehabilitation Hospital
by: Emilia Salvadori, et al.
Published: (2020-12-01)

Applicability of URANS and DES Simulations of Flow Past Rectangular Cylinders and Bridge Sections
by: Claudio Mannini
Published: (2015-09-01)

Degradation of EEG microstates patterns in subjective cognitive decline and mild cognitive impairment: Early biomarkers along the Alzheimer’s Disease continuum?
by: Michael Lassi, et al.
Published: (2023-01-01)

Dual Effect of <i>PER2</i> C111G Polymorphism on Cognitive Functions across Progression from Subjective Cognitive Decline to Mild Cognitive Impairment
by: Salvatore Mazzeo, et al.
Published: (2021-04-01)

PRedicting the EVolution of SubjectIvE Cognitive Decline to Alzheimer’s Disease With machine learning: the PREVIEW study protocol
by: Salvatore Mazzeo, et al.
Published: (2023-08-01)

Effects in Short and Long Term of Global Postural Reeducation (GPR) on Chronic Low Back Pain: A Controlled Study with One-Year Follow-Up
by: Chiara Castagnoli, et al.
Published: (2015-01-01)

Progressive Unspecified Motor Speech Disorder: A Longitudinal Single Case Study of an Older Subject
by: Benedetta Basagni, et al.
Published: (2022-04-01)

Predicting outcome of patients with prolonged disorders of consciousness using machine learning models based on medical complexity
by: Piergiuseppe Liuzzi, et al.
Published: (2022-08-01)

The Brain-Derived Neurotrophic Factor Val66Met Polymorphism Can Protect Against Cognitive Impairment in Multiple Sclerosis
by: Emilio Portaccio, et al.
Published: (2021-03-01)

The two cut‐offs approach for plasma p‐tau217 in detecting Alzheimer's disease in subjective cognitive decline and mild cognitive impairment
by: Giulia Giacomucci, et al.
Published: (2025-04-01)

Gender differences in cognitive reserve: An impact on progression in subjective cognitive decline?
by: Giulia Giacomucci, et al.
Published: (2025-07-01)

Beyond language: empathy and emotion recognition deficits in primary progressive aphasias
by: Giulia Giacomucci, et al.
Published: (2025-01-01)

Combining Gamma tACS stimulation with Robotic Rehabilitation after stroke in mice: the role of Parvalbumin Interneurons
by: Cristina Spalletti, et al.
Published: (2023-01-01)

Multiple Electroencephalogram Recordings for Monitoring the Evolution of Neurological Complications during Baclofen Withdrawal Syndrome
by: Maenia Scarpino, et al.
Published: (2022-01-01)