Postoperative pulmonary complications in acute type A aortic dissection

Abstract Objective The objective of this study was to identify the perioperative risk factors associated with postoperative pulmonary complications (PPCs) following emergency surgery for Acute Type A Aortic Dissection (ATAAD) and to evaluate the impact of these complications on short- and long-term...

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Published in:BMC Surgery
Main Authors: Pengfei Chen, Haochao Li, Chenyu Liu, Mingjian Chen, Diming Zhao, Liang Chen, Xiangyang Qian, Jundong Pu, Zujun Chen, Yuetang Wang, Liqing Wang
Format: Article
Language:English
Published: BMC 2025-07-01
Subjects:
Online Access:https://doi.org/10.1186/s12893-025-03062-w
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author Pengfei Chen
Haochao Li
Chenyu Liu
Mingjian Chen
Diming Zhao
Liang Chen
Xiangyang Qian
Jundong Pu
Zujun Chen
Yuetang Wang
Liqing Wang
author_facet Pengfei Chen
Haochao Li
Chenyu Liu
Mingjian Chen
Diming Zhao
Liang Chen
Xiangyang Qian
Jundong Pu
Zujun Chen
Yuetang Wang
Liqing Wang
author_sort Pengfei Chen
collection DOAJ
container_title BMC Surgery
description Abstract Objective The objective of this study was to identify the perioperative risk factors associated with postoperative pulmonary complications (PPCs) following emergency surgery for Acute Type A Aortic Dissection (ATAAD) and to evaluate the impact of these complications on short- and long-term patient outcomes. Methods A retrospective observational analysis was conducted on 750 adult patients who underwent emergency surgery for ATAAD between January 2017 and December 2019. Results The overall in-hospital mortality was 5.7%. Among 750 patients, 91 patients(12.1%) developed PPCs. Multivariable logistic regression analysis indicated that smoking(OR = 2.212, 95%CI: 1.361–3.595, P = 0.001), previous cardiac surgery(OR = 2.818, 95%CI: 1.259–6.310, P = 0.012), CPB time(OR = 1.003, 95%CI: 1.000–1.006, P = 0.047), and red blood cell transfusion(OR = 1.091, 95%CI: 1.059–1.124, P < 0.001) were associated with an increased risk of developing PPCs. Patients who developed PPCs had a higher 30-day mortality rate (P < 0.001), longer lengths of stay in the ICU and hospital(P < 0.001), increased healthcare costs(P < 0.001), and lower long-term survival rates(P = 0.005). Conclusion The incidence of PPCs is high in patients undergoing cardiac surgery for aortic dissection, adversely affecting their prognosis. This study identified four key risk factors associated with the development of PPCs.
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spelling doaj-art-e331ca9da7904364927351b286a0e7162025-08-20T03:42:26ZengBMCBMC Surgery1471-24822025-07-012511810.1186/s12893-025-03062-wPostoperative pulmonary complications in acute type A aortic dissectionPengfei Chen0Haochao Li1Chenyu Liu2Mingjian Chen3Diming Zhao4Liang Chen5Xiangyang Qian6Jundong Pu7Zujun Chen8Yuetang Wang9Liqing Wang10Cardiovascular Surgery Department, Fuwai Hospital, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, National Center for Cardiovescular DiseasesCardiovascular Surgery Department, Fuwai Hospital, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, National Center for Cardiovescular DiseasesCardiovascular Surgery Department, Fuwai Hospital, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, National Center for Cardiovescular DiseasesCardiovascular Surgery Department, Fuwai Hospital, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, National Center for Cardiovescular DiseasesCardiovascular Surgery Department, Fuwai Hospital, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, National Center for Cardiovescular DiseasesCardiovascular Surgery Department, Fuwai Hospital, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, National Center for Cardiovescular DiseasesCardiovascular Surgery Department, Fuwai Hospital, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, National Center for Cardiovescular DiseasesIntensive Care Unit, Dali Bai Autonomous Prefecture People’s HospitalCardiovascular Surgery Department, Fuwai Hospital, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, National Center for Cardiovescular DiseasesCardiovascular Surgery Department, Fuwai Hospital, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, National Center for Cardiovescular DiseasesCardiovascular Surgery Department, Fuwai Hospital, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, National Center for Cardiovescular DiseasesAbstract Objective The objective of this study was to identify the perioperative risk factors associated with postoperative pulmonary complications (PPCs) following emergency surgery for Acute Type A Aortic Dissection (ATAAD) and to evaluate the impact of these complications on short- and long-term patient outcomes. Methods A retrospective observational analysis was conducted on 750 adult patients who underwent emergency surgery for ATAAD between January 2017 and December 2019. Results The overall in-hospital mortality was 5.7%. Among 750 patients, 91 patients(12.1%) developed PPCs. Multivariable logistic regression analysis indicated that smoking(OR = 2.212, 95%CI: 1.361–3.595, P = 0.001), previous cardiac surgery(OR = 2.818, 95%CI: 1.259–6.310, P = 0.012), CPB time(OR = 1.003, 95%CI: 1.000–1.006, P = 0.047), and red blood cell transfusion(OR = 1.091, 95%CI: 1.059–1.124, P < 0.001) were associated with an increased risk of developing PPCs. Patients who developed PPCs had a higher 30-day mortality rate (P < 0.001), longer lengths of stay in the ICU and hospital(P < 0.001), increased healthcare costs(P < 0.001), and lower long-term survival rates(P = 0.005). Conclusion The incidence of PPCs is high in patients undergoing cardiac surgery for aortic dissection, adversely affecting their prognosis. This study identified four key risk factors associated with the development of PPCs.https://doi.org/10.1186/s12893-025-03062-wAcute type A aortic dissectionPostoperative pulmonary complicationsCardiac surgery
spellingShingle Pengfei Chen
Haochao Li
Chenyu Liu
Mingjian Chen
Diming Zhao
Liang Chen
Xiangyang Qian
Jundong Pu
Zujun Chen
Yuetang Wang
Liqing Wang
Postoperative pulmonary complications in acute type A aortic dissection
Acute type A aortic dissection
Postoperative pulmonary complications
Cardiac surgery
title Postoperative pulmonary complications in acute type A aortic dissection
title_full Postoperative pulmonary complications in acute type A aortic dissection
title_fullStr Postoperative pulmonary complications in acute type A aortic dissection
title_full_unstemmed Postoperative pulmonary complications in acute type A aortic dissection
title_short Postoperative pulmonary complications in acute type A aortic dissection
title_sort postoperative pulmonary complications in acute type a aortic dissection
topic Acute type A aortic dissection
Postoperative pulmonary complications
Cardiac surgery
url https://doi.org/10.1186/s12893-025-03062-w
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