Development of Barrett's Esophagus Soon after Total Gastrectomy

The role of duodenal reflux and the time required for the development of Barrett's esophagus has remained controversial. We report a case of Barrett's esophagus that developed 6 months after total gastrectomy. A 76-year-old man diagnosed with gastric adenocarcinoma underwent a total gastre...

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Bibliographic Details
Published in:Gut and Liver
Format: Article
Language:English
Published: Gastroenterology Council for Gut and Liver 2008-06-01
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Online Access:http://gutnliver.org/journal/view.html?doi=10.5009/gnl.2008.2.1.51
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Summary:The role of duodenal reflux and the time required for the development of Barrett's esophagus has remained controversial. We report a case of Barrett's esophagus that developed 6 months after total gastrectomy. A 76-year-old man diagnosed with gastric adenocarcinoma underwent a total gastrectomy and a Roux- en-Y esophagojejunostomy. The gastroesophageal junction in the resected specimen was both grossly and microscopically normal at the time of the operation. A routine follow-up endoscopic examination performed 6 months later revealed a tongue-like projection of red- colored columnar tissue. No reflux symptoms (heartburn or acid regurgitation) had been present during the intervening 6 months. A biopsy specimen from the esophagus showed intestinal-type metaplasia of the columnar epithelium. This case supports the development of Barrett's esophagus solely from duodenal reflux and after a relatively short time in this clinical setting. (Gut and Liver 2008;2:51-53)
ISSN:1976-2283