Surgical-PEARL protocol: a multicentre prospective cohort study exploring aetiology, management and outcomes for patients with congenital anomalies potentially requiring surgical intervention

Introduction Congenital anomalies affect over 2% of pregnancies. Surgical advances have reduced mortality and improved survival for patients with congenital anomalies potentially requiring surgical (CAPRS) intervention. However, our understanding of aetiology, diagnostic methods, optimal management,...

Full description

Bibliographic Details
Published in:	BMJ Open
Main Authors:	Clare Skerritt, Massimo Caputo, Andrew Mumford, Karen Luyt, Mai Baquedano, Andrew R Bamber, Catherine Bradshaw, Deborah Lawlor, Samantha E de Jesus, Stuart Mires, Beverley Power, Hannah Gill, Tim Overton
Format:	Article
Language:	English
Published:	BMJ Publishing Group 2022-12-01
Online Access:	https://bmjopen.bmj.com/content/12/12/e066480.full

Similar Items

Radial head subluxation in a chondrodystrophic cat: aetiology, surgical treatment and outcome
by: Katharina Lunde, et al.
Published: (2025-09-01)

Outcome monitoring and risk stratification after cardiac procedure in neonates, infants, children and young adults born with congenital heart disease: protocol for a multicentre prospective cohort study (Children OMACp)
by: Orhan Uzun, et al.
Published: (2023-08-01)

God is in the Details: Surgical Pearl for Lower Lip Wedge Resection
by: Bruno Duarte, et al.
Published: (2019-07-01)

Open Globe Injuries: Review of Evaluation, Management, and Surgical Pearls
by: Zhou Y, et al.
Published: (2022-08-01)

Surgical Management of Male Stress Incontinence: Techniques, Indications, and Pearls for Success
by: Smith WJ, et al.
Published: (2023-06-01)

Improving Surgical Techniques: Use of Surgical Procedures Videos as Learning Tools - A Multicentric Study
by: Ahmed Hassaan Malik, et al.
Published: (2024-08-01)

Aetiology of Pleural Effusions in a Large Multicentre Cohort: Variation Between Outpatients and Inpatients
by: Asfandyar Yousuf, et al.
Published: (2024-10-01)

MULTICENTRIC EARLY GASTRIC CANCER: CURRENT APPROACHES TO SURGICAL TREATMENT
by: M. I. Davydov, et al.
Published: (2016-02-01)

Expanding Horizons of Cervical Endoscopic Spine Surgery: Important Surgical Landmarks and Technical Pearls
by: Jayesh Sardhara, et al.
Published: (2022-01-01)

Attitudes of Canadian medical students towards surgical training and perceived barriers to surgical careers: a multicentre survey
by: Steffane McLennan, et al.
Published: (2023-06-01)

Validation of insurance claims data on aetiology, surgical type and prosthesis for isolated valve surgery: a retrospective observational surgery
by: Shao-Wei Chen, et al.
Published: (2025-02-01)

Surgical techniques and pearls for revisional plantar fibroma resection and medial plantar nerve decompression and implantation
by: Chloe F. Sakow, DPM, MPH, et al.
Published: (2024-01-01)

Surgical impact of BRAF-inhibitor therapy in the treatment of melanoma brain metastases. An observational multicentric study about surgical features and outcome
by: Dr. Daniele Armocida, et al.
Published: (2025-01-01)

Greater Trochanteric Pain Syndrome: An Intraoperative Endoscopic Classification System with Pearls to Surgical Techniques and Rehabilitation Protocols
by: Ajay C. Lall, M.D., M.S., et al.
Published: (2019-08-01)

A protocol for the conduct of a multicentre, prospective, randomized superiority trial of surgical versus non-surgical interventions for humeral shaft fractures: the HUmeral SHaft (HUSH) fracture study
by: Marloes Franssen, et al.
Published: (2024-04-01)

Identification of priority pathogens for aetiological diagnosis in adults with community-acquired pneumonia in China: a multicentre prospective study
by: Lulu Zhang, et al.
Published: (2023-04-01)

Surgical versus non-surgical management of orbital fractures: study protocol for evidence generation of a prospective multicentre observational cohort registry
by: Eppo B Wolvius, et al.
Published: (2025-07-01)

Reconstruction of Moderately and Severely Atrophic Scalp—A Multicentric Experience in Surgical Treatment of Patients Irradiated for Tinea Capitis in Childhood and Surgical Algorithm
by: Maja Nikolić Živanović, et al.
Published: (2023-09-01)

Plantar heel pain: an update of its aetiology and diagnosis
by: Karl B Landorf, et al.
Published: (2013-01-01)

Microbiologic Evaluation of Colorectal Surgical Site Infections to Guide Surgical Prophylaxis Recommendations
by: Ardath Plauche, et al.
Published: (2024-07-01)

Geographic variation in the aetiology, epidemiology and microbiology of bronchiectasis
by: Ravishankar Chandrasekaran, et al.
Published: (2018-05-01)

Long-term outcome of surgical management in neovascular glaucoma: A retrospective, multicentric study
by: Julie Pegu, et al.
Published: (2025-03-01)

Differences in surgical outcomes between cervical goiter and retrosternal goiter: an international, multicentric evaluation
by: Federico Cappellacci, et al.
Published: (2024-02-01)

Paediatric surgical outcomes in sub-Saharan Africa: a multicentre, international, prospective cohort study
by: Niyi Ade-Ajayi, et al.
Published: (2021-09-01)

Aetiology of acute respiratory infection in preschool children requiring hospitalisation in Europe—results from the PED-MERMAIDS multicentre case–control study
by: Cristina Calvo, et al.
Published: (2021-01-01)

Severe acute hepatitis of unknown aetiology in children—what is known?
by: Susan Khader, et al.
Published: (2022-07-01)

Aetiology of urticaria in children
by: S. N. Buinova, et al.
Published: (2017-09-01)

Prevention and Aetiology of Burns
by: R. N. Sinha
Published: (1972-07-01)

Surgical outcomes of gallbladder cancer: the OMEGA retrospective, multicentre, international cohort studyResearch in context
by: Anita Balakrishnan, et al.
Published: (2023-05-01)

Multicentre randomised double-blind placebo controlled trial of combination vancomycin and cefazolin surgical antibiotic prophylaxis: the Australian surgical antibiotic prophylaxis (ASAP) trial
by: Allen C Cheng, et al.
Published: (2019-11-01)

Pre- and Post-Operative Cognitive Assessment in Patients Undergoing Surgical Aortic Valve Replacement: Insights from the PEARL Project
by: Valentina Fiolo, et al.
Published: (2024-10-01)

Surgical site infection after gastrointestinal surgery in children: an international, multicentre, prospective cohort study
by: Nebyou Seyoum, et al.
Published: (2020-12-01)

Editorial: The Developments of Hybrid Surgical Strategies for Congenital Heart Disease
by: Filippo Rapetto, et al.
Published: (2017-09-01)

TBXA2R gene variants associated with bleeding
by: Stuart James Mundell, et al.
Published: (2018-10-01)

Burnout and personality factors among surgical area nurses: a cross sectional multicentre study
by: Almudena Velando-Soriano, et al.
Published: (2024-07-01)

Impact of COVID-19 on ophthalmic surgical procedures in sub-Saharan Africa: a multicentre study
by: Naseer Ally, et al.
Published: (2024-03-01)

Intracranial Meningioma in Elderly Patients. Retrospective Multicentric Risk and Surgical Factors Study of Morbidity and Mortality
by: Daniele Armocida, et al.
Published: (2022-01-01)

Total colonic aganglionosis: multicentre study of surgical treatment and patient‐reported outcomes up to adulthood
by: P. Stenström, et al.
Published: (2020-10-01)

A Comparative Multicentric Study on Serosal and Endometrial Myomectomy During Cesarean Section: Surgical Outcomes
by: Şafak Hatırnaz, et al.
Published: (2021-08-01)

Ethical considerations in the era of AI, automation, and surgical robots: there are plenty of lessons from the past
by: David Power
Published: (2024-10-01)