Biologics for generalized pustular psoriasis: a systematic review and single-arm meta-analysis

IntroductionGeneralized pustular psoriasis (GPP) is a rare and potentially life-threatening auto-inflammatory disease. Currently, there are no consensus-based guidelines or universally accepted treatments. Biologics represent a potential therapeutic option. This study systematically assessed the eff...

Full description

Bibliographic Details
Published in:	Frontiers in Immunology
Main Authors:	Bai-lin Chen, Qian-wei Liu, Xiao-wan Dong, Yan-ping Bai
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-10-01
Subjects:	generalized pustular psoriasis biologics systematic review meta-analysis single-arm
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1462158/full

Similar Items

Serious generalized pustular psoriasis with evolution to plaque psoriasis: approach with spesolimab
by: Liz S. Gea, et al.
Published: (2024-10-01)

Characteristics of Patients with Generalized Pustular Psoriasis: A Report of the Polish Generalized Pustular Psoriasis Group
by: Marta Kołt-Kamińska, et al.
Published: (2024-11-01)

Pustular Psoriasis: From Pathophysiology to Treatment
by: Giovanni Genovese, et al.
Published: (2021-11-01)

Pustular psoriasis of pregnancy: current perspectives
by: Trivedi MK, et al.
Published: (2018-02-01)

Phenotypic differences in clinical manifestations of generalized pustular psoriasis and severe plaque psoriasis in tropical Taiwan
by: Yin-Cheng Chao, et al.
Published: (2024-09-01)

Pustular Psoriasis: The Dawn of a New Era
by: Hervez Bachelez
Published: (2020-01-01)

The update of treatment strategies in pediatrics with generalized pustular psoriasis in China
by: Yunliu Chen, et al.
Published: (2023-09-01)

Generalized Pustular Psoriasis During Early Pregnancy Successfully Treated with Spesolimab: A Case Report
by: Chen X, et al.
Published: (2025-05-01)

Characteristics of Patients Experiencing a Flare of Generalized Pustular Psoriasis: A Multicenter Observational Study
by: Francesco Bellinato, et al.
Published: (2023-03-01)

Monotherapy with Biologics for Generalized Pustular Psoriasis: A Systematic Review of Comparative Interventional Studies with an Exploratory Network Meta-Analysis
by: Aditya K. Gupta, et al.
Published: (2026-06-01)

Generalized Pustular Psoriasis in Childhood: A Rare Case
by: vella Asnawi, et al.
Published: (2023-11-01)

Diagnostic difficulties in a patient with generalized pustular psoriasis
by: Katarzyna Juczyńska
Published: (2014-11-01)

Association between the neutrophil percentage-to-albumin ratio and generalized pustular psoriasis
by: Arisa Yoshimura, et al.
Published: (2025-08-01)

Clinical efficacy and safety of secukinumab in the treatment of generalized pustular psoriasis in the pediatric population: a systematic review of the literature
by: Kebo Wei, et al.
Published: (2024-08-01)

Severe Generalized Pustular Psoriasis Successfully Treated with Ixekizumab: A Case Report
by: Martina Burlando, et al.
Published: (2022-11-01)

Successful treatment of recalcitrant generalized pustular psoriasis of pregnancy with spesolimab
by: Chenxin Yang, et al.
Published: (2024-12-01)

The Uncommon Coexistence of Mid-Borderline Leprosy and Generalized Pustular Psoriasis
by: Gunawan H, et al.
Published: (2026-04-01)

Prevalence and incidence of patients with generalized pustular psoriasis in Denmark—A nationwide registry‐based study
by: Jeanette Halskou Haugaard, et al.
Published: (2023-12-01)

Terbinafine-induced generalized pustular psoriasis treated with dapsone
by: Matilde Monteiro, et al.
Published: (2025-04-01)

Generalized annular pustular psoriasis (Milian‐Katchoura type) induced by systemic steroids
by: Madiha El Jazouly, et al.
Published: (2021-04-01)

Clinical Characteristics of Patients with Pustular Psoriasis: A Single-Center Retrospective Observational Study
by: Paolo Gisondi, et al.
Published: (2022-07-01)

Abrocitinib Treatment for Localized Type of Generalized Pustular Psoriasis: A Case Report
by: Yang Z, et al.
Published: (2025-03-01)

Generalized pustular psoriasis successfully treated with spesolimab in the setting of metastatic colon cancer
by: Diamond Rose Guy, BS, et al.
Published: (2024-08-01)

Case report: Efficacy of tofacitinib in the treatment of generalized pustular psoriasis
by: Xian Wang, et al.
Published: (2025-02-01)

Commentary: Unmet Needs in Generalized Pustular Psoriasis in Clinical Practice
by: Anna Balato, et al.
Published: (2023-12-01)

Severe paradoxical generalized pustular psoriasis induced by adalimumab biosimilar successfully treated with brodalumab
by: Angela Fico, et al.
Published: (2025-05-01)

Clinical Characteristics and Disease Burden of Patients with Moderate-to-Severe Generalized Pustular Psoriasis Flares in Taiwan
by: Chun-Wei Lu, et al.
Published: (2024-07-01)

Generalized Pustular Psoriasis Brazilian Experts Survey: Challenges in Disease Management
by: Ricardo Romiti, et al.
Published: (2025-04-01)

Characteristics and Outcomes of Generalized Pustular Psoriasis Patients Managed Through Inpatient Asynchronous Teledermatology: A Retrospective Study
by: Jeffrey Chen, et al.
Published: (2025-01-01)

Natalizumab-Induced Pustular Psoriasis of Palms and Soles
by: Bengisu Ozarslan, et al.
Published: (2022-05-01)

Successful treatment of generalized pustular psoriasis with guselkumab
by: Martina Part
Published: (2024-12-01)

Generalized pustular psoriasis: a multicentric study on patient characteristics and clinical burden
by: Cristina Bulai Livideanu, et al.
Published: (2025-02-01)

Crusted Scabies in a Patient being Treated with Spesolimab for Generalized Pustular Psoriasis
by: Hanna Schratter, et al.
Published: (2025-02-01)

Skin microbiota in patients with psoriasis vulgaris and pustular psoriasis
by: E. A. Bakhlykova, et al.
Published: (2017-08-01)

Generalized Pustular Psoriasis with Breast Cancer Successfully Treated with Spesolimab Causing Neutrophilia: A Case Report
by: Rina Obata, et al.
Published: (2025-03-01)

Real-Life Analysis of Therapeutic Management and Its Correlation With the Dermatology Life Quality Index Score in 108 Patients With Pustular Psoriasis: An Italian Monocenter Study
by: Dario Buononato, et al.
Published: (2025-01-01)

Use of Biological Therapies for the Management of Pustular Psoriasis: A New Era?
by: Megna M, et al.
Published: (2023-06-01)

Treatment of generalized pustular psoriasis with Spesolimab: a case report and literature review
by: Xiaoqian LIANG, et al.
Published: (2024-05-01)

Real-world efficacy of spesolimab in treating generalized pustular psoriasis flares: A case series review
by: Chun-Bing Chen, et al.
Published: (2025-04-01)

Case Report: Successful treatment of refractory generalized pustular psoriasis with xeligekimab: a report of two cases
by: Xiao Zang, et al.
Published: (2026-06-01)