Green tea polyphenols, epicatechin gallate and epigallocatechin gallate, alleviated aberrant metabolic changes caused by olanzapine in rats

Objective: Olanzapine, a well-known antipsychotic drug, causes considerable weight gain and metabolic abnormalities in patients. Green tea (Camellia sinensis) has anti-obesity, antihypertensive, antihyperlipidemic, and anti-diabetes effects. The aim of this study was to investigate the potential eff...

Full description

Bibliographic Details
Published in:	Avicenna Journal of Phytomedicine
Main Authors:	Elmira Hoseini, Bibi Marjan Razavi, Mohaddeseh Sadat Alavi, Hossein Hosseinzadeh, Ali Roohbakhsh
Format:	Article
Language:	English
Published:	Mashhad University of Medical Sciences 2025-09-01
Subjects:	olanzapine metabolic syndrome green tea epigallocatechin gallate epicatechin gallate
Online Access:	https://ajp.mums.ac.ir/article_25926_9bb8db98b10012d75147f0d71637bdee.pdf

Similar Items

Assessment of Extraction Parameters on Antioxidant Capacity, Polyphenol Content, Epigallocatechin Gallate (EGCG), Epicatechin Gallate (ECG) and Iriflophenone 3-C-β-Glucoside of Agarwood (Aquilaria crassna) Young Leaves
by: Pei Yin Tay, et al.
Published: (2014-08-01)

Epicatechin Gallate Decreases the Viability and Subsequent Embryonic Development of Mouse Blastocysts
by: Hsiao-Chen Tu, et al.
Published: (2010-06-01)

The Effects of Green Tea Catechins in Hematological Malignancies
by: Fernanda Isabel Della Via, et al.
Published: (2023-07-01)

TLC separation of methylated (-)-epigallocatechin-3-gallate
by: Ryszard Amarowicz, et al.
Published: (2005-02-01)

Therapeutic effects of epigallocatechin and epigallocatechin gallate on the allergic reaction of αs1-casein sensitized mice
by: Qianqian Zhang, et al.
Published: (2023-05-01)

Epigallocatechin gallate: a review
by: L. Bartosikova, et al.
Published: (2018-10-01)

Epicatechin Gallate Regulation of Steroid Hormone Levels Improves Sarcopenia in C57BL/6J Mice
by: Ziwei Huang, et al.
Published: (2025-07-01)

Effect of (−)-Epigallocatechin Gallate to Staphylococcal Enterotoxin A on Toxin Activity
by: Yuko Shimamura, et al.
Published: (2020-04-01)

The effect of pH on structural properties and interaction mechanisms of zein/epicatechin gallate complexes
by: Xiujuan Chen, et al.
Published: (2024-12-01)

Reactive Carbonyl Species Scavenger: Epigallocatechin-3-Gallate
by: Haiying Luo, et al.
Published: (2024-03-01)

Targeting aging pathways with natural compounds: a review of curcumin, epigallocatechin gallate, thymoquinone, and resveratrol
by: Mohamed Ahmed
Published: (2025-07-01)

Efficacy and Safety of Epigallocatechin Gallate in the Treatment and Prevention of Dermatitis: A Systematic Review
by: Katarzyna Śladowska, et al.
Published: (2025-06-01)

Epigallocatechin-3-Gallate Therapeutic Potential in Cancer: Mechanism of Action and Clinical Implications
by: Mateusz Kciuk, et al.
Published: (2023-07-01)

Epigallocatechin-3-gallate reduces inflammation induced by calcium pyrophosphate crystals in vitro.
by: Francesca eOliviero, et al.
Published: (2013-04-01)

Curcumin and (−)- Epigallocatechin-3-Gallate Protect Murine MIN6 Pancreatic Beta-Cells against Iron Toxicity and Erastin-Induced Ferroptosis
by: Tugba Kose, et al.
Published: (2019-02-01)

Gallic Acid Derivatives Propyl Gallate and Epigallocatechin Gallate Reduce rRNA Transcription via Induction of KDM2A Activation
by: Yuji Tanaka, et al.
Published: (2021-12-01)

The effect of epigallocatechin gallate on Streptococcus Gordonii biofilm formation
by: Dimas Prasetianto Wicaksono, et al.
Published: (2024-12-01)

Computational study unravels inhibitory potential of epicatechin gallate against inflammatory and pyroptosis‐associated mediators in COVID‐19
by: Prem Rajak, et al.
Published: (2023-06-01)

The Effect of Nano-Epigallocatechin-Gallate on Oxidative Stress and Matrix Metalloproteinases in Experimental Diabetes Mellitus
by: Adriana Elena Bulboaca, et al.
Published: (2020-02-01)

Carboplatin and epigallocatechin-3-gallate synergistically induce cytotoxic effects in esophageal cancer cells
by: Fatemeh Taghvaei, et al.
Published: (2021-01-01)

Epigallocatechin Gallate-Modified Silver Nanoparticles Show Antiviral Activity against Herpes Simplex Type 1 and 2
by: Malgorzata Krzyzowska, et al.
Published: (2023-09-01)

Protective Effect of Liposomal Epigallocatechin-Gallate in Experimental Gentamicin-Induced Hepatotoxicity
by: Adriana Elena Bulboacă, et al.
Published: (2022-02-01)

Health promoting activities and corresponding mechanism of (–)-epicatechin-3-gallate
by: Zhiliang Li, et al.
Published: (2022-05-01)

Heat treatment effect on whey protein–epigallocatechin gallate interaction: A fluorescence spectroscopic analysis
by: Yu-qi Song, et al.
Published: (2023-12-01)

Dopamine and epigallocatechin-3-gallate cross-linked coating demonstrates improved osteointegration of polyetheretherketone in rabbits
by: Genwen Mao, et al.
Published: (2023-02-01)

The roles of epigallocatechin gallate in the tumor microenvironment, metabolic reprogramming, and immunotherapy
by: Dongming Li, et al.
Published: (2024-01-01)

Epigallocatechin-3-gallate and cancer: focus on the role of microRNAs
by: Chunguang Wang, et al.
Published: (2023-10-01)

The cytotoxic mechanism of epigallocatechin gallate on proliferative HaCaT keratinocytes
by: Yu-Wen Chu, et al.
Published: (2017-08-01)

Antibacterial and antifungal activities of new acylated derivatives of epigallocatechin gallate
by: Yoshimi eMatsumoto, et al.
Published: (2012-02-01)

Mechanistic role of epigallocatechin-3-gallate in regulation of the antioxidant markers in ethanol induced liver damage in mice
by: Mujinya Pastori, et al.
Published: (2022-12-01)

ANTIOXIDATIVE EFFECT OF EPIGALLOCATECHIN GALLATE AGAINST D-GALACTOSAMINE-INDUCED INJURY IN PRIMARY CULTURE OF RAT HEPATOCYTES
by: Alena Moravcová, et al.
Published: (2014-01-01)

Preparation of chitosan-Epigallocatechin-3-O-gallate nanoparticles and their inhibitory effect on the growth of breast cancer cells
by: Yingyi Liu, et al.
Published: (2018-07-01)

Beneficial Effects of Epigallocatechin Gallate in Preventing Skin Photoaging: A Review
by: Jiaqiang Sun, et al.
Published: (2024-11-01)

Epigallocatechin Gallate Attenuates Gentamicin-Induced Nephrotoxicity by Suppressing Apoptosis and Ferroptosis
by: Lin Yue, et al.
Published: (2022-12-01)

Green Tea Polyphenol Epigallocatechin-Gallate in Amyloid Aggregation and Neurodegenerative Diseases
by: Luiza Fernandes, et al.
Published: (2021-09-01)

Epigallocatechin-gallate loaded BSA nanoparticles as innovative anti-inflammatory agents in immature macrophages
by: Simona Martano, et al.
Published: (2025-10-01)

An epigallocatechin gallate–amorphous calcium phosphate nanocomposite for caries prevention and demineralized enamel restoration
by: Danni Dai, et al.
Published: (2023-08-01)

Epigallocatechin gallate modulates ferroptosis through downregulation of tsRNA-13502 in non-small cell lung cancer
by: Shun Wang, et al.
Published: (2024-06-01)

Chemical bonding of Epigallocatechin-3-gallate to the surface of nano-hydroxyapatite to enhance its biological activity for anti-osteosarcoma
by: Jian Ren, et al.
Published: (2023-01-01)

Enhancing Antibiotics Efficacy by Combination of Kuraridin and Epicatechin Gallate with Antimicrobials against Methicillin-Resistant <i>Staphylococcus aureus</i>
by: Ben Chung-Lap Chan, et al.
Published: (2023-01-01)