Assessment of Protective Effect of Turmeric on Aspirin Induced Gastric Injury on Wistar Rats

• Published in: Journal of Applied Sciences and Environmental Management
• Main Authors: F. F. Akeredolu, A. A. Oladele, V. O. Ekundina
• Format: Article
• Language: English
• Published: Joint Coordination Centre of the World Bank assisted National Agricultural Research Programme (NARP) 2022-10-01
• Subjects: Turmeric; Aspirin; Stomach; Histology; Histochemistry
• Online Access: https://www.ajol.info/index.php/jasem/article/view/234722

Turmeric (from Zingiberaceae family) is highly regarded as a universal panacea in the herbal medicine with a wide spectrum of pharmacological activities. Forty eight adult rats (150g-200g body weight) were randomly divided into six (control, treatment, 3 post treatment and recovery) groups of eight rats each. Gastric injury were induced with the administration of different concentration of Aspirin and co treated with different concentration of Turmeric for a period of 14-28 days. It was histologically revealed that Aspirin can induced gastric injury and Turmeric protect gastric layers. There is need for more research work on the protective effect of Turmeric on gastric layers against gastric injury.