A mechanical model for lateral and axial impacts and quantification of effect on viability of SHSY5Y neuroblastoma cells

Abstract Current research indicates that neuronal cells exhibit morphological alterations when subjected to mechanical force, yet the correlation between cellular shape modification and applied force remains ambiguous. Here, we apply mechanical impact on neuroblastoma SHSY5Y 2D-cultured cells and ob...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Raisa Akhtaruzzaman, Kamal Awad, Arthur Koster, Venu Varanasi, Marco Brotto, Ashfaq Adnan
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-06-01
Subjects:	Morphological change Traumatic brain injury SHSY5Y neuroblastoma cell Cytoskeleton damage Spring-Dashpot system Mechanical modelling
Online Access:	https://doi.org/10.1038/s41598-025-02165-x